不同消毒液对胃肠道吻合口愈合的影响  

Impact of different disinfectant on healing of gastrointestinal tract anastomosis

作　　者：林卫红[1] 陈丽莉[1] 季晓克[1] 曾其强[1] 钱黄静[1] 张启瑜[1] 

机构地区：[1]温州医学院附属第一医院手术室,浙江温州325000

出　　处：《中华医院感染学杂志》2011年第2期302-303,共2页Chinese Journal of Nosocomiology

摘　　要：目的探讨不同消毒液对胃肠道吻合口愈合的影响及影响程度,试图筛选出适合胃肠道吻合口的最佳消毒方法。方法对50只家兔实行胃-空肠、空肠-空肠单层缝合,随机分成5组,分别用不同消毒液消毒拟吻合组织黏膜;并在术后3、7 d取家兔腹水大肠埃希菌测定,在术后3、71、0 d留取吻合口标本检测吻合口破裂压、吻合口组织中胶原纤维含量测定。结果 5组死亡数差异无统计学意义;生理盐水组、乙醇组、聚维酮碘组、碘酊组和氯己定组腹水大肠埃希菌测定:术后3 d检测阳性率分别为50.0%、33.3%、11.1%、30.0%和22.2%,差异无统计学意义,术后7 d检测阳性率分别为80.0%、55.6%、22.2%、60.0%、88.9%,差异有统计学意义(P<0.01,χ2=34.55)。结论不同消毒液对胃肠道吻合口愈合的影响不同,聚维酮碘是胃肠道吻合口消毒最为理想的消毒液。OBJECTIVE To investigate the effects of different disinfection solutions on the healing of single-layer gastrointestinal tract anastomosis,and find out the best one for disinfecting gastrointestinal tract anastomotic stoma.METHODS Totally 5o cases were performed with gastric-jejunum single-layer anastomosis or jejunum-jejunum single-layer anastomosis.The fifty cases were randomly divided into five groups.The Escherichia coli was determined in ascites of rabbits of all groups on the day 3 and 7 postoperatively,respectively.The anastomostic bursting pressures（ABP） and collagen fiber content of anastomotic stoma in all groups were determined on the day 3,7 and 10 postoperatively,respectively.RESULTS There was no significant difference among the 5 groups in the death rates and the positive rates of post-operation for 3 days were 50.0%,33.3%,11.1%,30.0% and 22.2%,respectively,and the positive rates of post-operation for 7 days were 80.0%,55.6%,22.2%,60.0% and 88.9%,respectively.CONCLUSION Different disinfectant have different effects on the healing of single-layer gastrointestinal tract anastomosis,and Povidone Iodine maybe the perfect one.

关 键 词：不同消毒液 胃肠道 吻合口愈合 影响 

分 类 号：R187[医药卫生—流行病学]