综合ICU患者获得性医院感染病原菌耐药性及干预对策  

Drug resistance of pathogens causing hospital-acquired infection in comprehensive ICU and intervention strategy

作　　者：鲁艳[1] 程利民[1] 胡艳华[2] 

机构地区：[1]孝感市中心医院院内感染控制办公室,湖北孝感432000 [2]孝感市中心医院院儿科注射室,湖北孝感432000

出　　处：《中华医院感染学杂志》2011年第2期337-338,共2页Chinese Journal of Nosocomiology

摘　　要：目的探讨医院综合ICU患者获得性医院感染病原菌的耐药现状,并制定针对性干预对策。方法调查分析ICU获得性医院感染患者的病历资料;了解其病原菌耐药率。结果医院感染的257株病原菌中居前5位依次为铜绿假单胞菌、鲍氏不动杆菌、肺炎克雷伯菌、金黄色葡萄球菌、大肠埃希菌,分别占18.3%、17.5%、14.4%、14.4%、8.9%,耐甲氧西林金黄色葡萄球菌(MRSA)检出率为40.5%;病原菌对常用抗菌药物均产生了较严重的耐药性。结论综合ICU应采取行之有效的干预对策,控制细菌耐药性迅速增长的不良趋势。OBJECTIVE To investigate antimicrobial resistance status of pathogens causing hospital-acquired infection in ICU and institute intervention strategy.METHODS The clinical data of patients with hospital-acquired infection were analyzed to understand the antimicrobial resistance rate.RESULTS Among 257 strains of pathogens causing nosocomial infection,the top five pathogens were Pseudomonas aeruginosa,Acinatobacter baumannii,Klebsiella pneunmoniae,Staphylococcus aureus and Escherichia coli accounting for 18.3%,17.5%,14.4%,14.4%,8.9%.The detection rate of methicillin-resistant S.aureus（MRSA） was 40.5%.The serious antimicrobial resistance of commonly used antibiotics occurred in pathogens.CONCLUSION The effective intervention strategy should be adopted to control the increasing tendency of bacterial drug resistance.

关 键 词：综合重症监护病房 医院感染 病原菌 耐药性 干预对策 

分 类 号：R378[医药卫生—病原生物学]