复方斯亚旦生发酊促大鼠毛发生长实验研究  

Study on Hair Growth Effects in Rats of Compound Siyadan Tincture

作　　者：赵海娇[1] 王园姬[1] 任全霞[1] 李桂华[1] 陈文[1,2] 

机构地区：[1]新疆石河子大学药学院,新疆石河子832000 [2]新疆特种植物药资源教育部重点试验室,新疆石河子832000

出　　处：《中医药导报》2011年第1期20-21,24,共3页Guiding Journal of Traditional Chinese Medicine and Pharmacy

基　　金：国家科技支撑计划课题(2007BAI48B00)

摘　　要：目的:考察复方斯亚旦生发酊的生发作用。方法:对大鼠背部局部区域剃毛后,采用自身对照法,连续21 d给予不同浓度的复方斯亚旦生发酊及阳性药,分别以大鼠的给药区域毛长、毛重及显微镜下毛囊数为指标,考察各给药组对大鼠毛发的影响。结果:中、高剂量组与2%的米诺地尔组相比,差异具有统计学意义(P<0.05),且各给药组与95%乙醇组相比,差异均具有统计学意义(P<0.05);H-E染色后镜下观察,毛囊数与95%乙醇组相比,差异均具有统计学意义(P<0.05)。结论:复方斯亚旦生发酊具有一定的促大鼠毛发生长作用。Objective： To investigate the roles of Compound Siyadan Tincture in hair growth in rats.Methods： After shaving the hairs of rats partly,the methods of own control to rats was used and different concentration of Compound Siyadan Tincture and control drug were administered partly on the back of the rats for 21 days continuously.Then using the length,weight and the number of the hair follicles as the targets,the effects of Compound Siyadan Tincture in promoting hair growth were studied.Results： The middle and high dose groups showed significant difference compared with 2% minoxidil（P0.05）;each medication administration team showed significant difference compared with 95% ethanol group（P0.05）.Conclusion： Compound Siyadan Tincture had a good effect in promoting the hair growth of rats.

关 键 词：复方斯亚旦生法酊 毛发生长 

分 类 号：R285.5[医药卫生—中药学]