高效液相色谱法测定柴胡和黄芩配伍的化学成分变化  

Study on the changes of chemical components in compatibility of Radix Bupleuri with Radix Scutellariae

作　　者：念其滨[1] 刘洪旭[2] 邓思珊[2] 马振菁[2] 黄巧文[3] 

机构地区：[1]福建省级机关医院药剂科,福建福州350003 [2]福建省医学科学研究所,福建福州350001 [3]福建省人民医院,福建福州350004

出　　处：《中国医院药学杂志》2011年第2期104-107,共4页Chinese Journal of Hospital Pharmacy

摘　　要：目的:研究柴胡和黄芩配伍后化学成分在质和量上的变化。方法:采用HPLC法比较柴胡-黄芩单煎液与合煎液中各成分的变化。结果:柴胡-黄芩配伍后大多数化学成分在质和量上没有变化,少数化学成分含量发生了增减变化,发现有成分种类的减少,但未发现增加。结论:中药复方的配伍并不是单味中药的简单相加,而是有一定科学依据的。OBJECTIVE To study the changes of quality and quantity of chemical components in compatibility of Radix Bupleuri with Radii Scutellariae. METHODS HPLC was used to delermine and to analyze the peaks change of chemical components of single and co-decoction. RESULTS There were fewer changed in most chemical components of co-decodtion than single decodtion. The quantity of some components were lowered, and the peak would disappreared after the co decoction , but no peak increased was found. CONCLUSION The compatibility of traditional chinese medicine is not the simple adding of single herbs, but it in volves some scientific base.

关 键 词：高效液相色谱法 黄芩 柴胡 配伍 化学成分 

分 类 号：R927[医药卫生—药学]