正交设计法优选虎杖中白藜芦醇水提取工艺  

Orthogonal design of water extraction technique of resveratrol in Polygonum cuspidatum

作　　者：夏海武[1] 战克勤[2] 许娜[1] 赵岩[1] 

机构地区：[1]安徽科技学院,安徽凤阳233100 [2]潍坊市人民医院,山东潍坊261061

出　　处：《中国医院药学杂志》2011年第2期123-124,125,共3页Chinese Journal of Hospital Pharmacy

基　　金：安徽科技学院人才专项(编号:ZRC200692)

摘　　要：目的:考查虎杖中白藜芦醇的提取工艺。方法:采用L9(34)正交试验设计,以白藜芦醇提取率为考察指标,考察加水量、提取温度、提取时间等因素对提取工艺的影响。结果:以加水量为药材量的20倍,提取温度为60℃,提取时间为每次12h,为虎杖白藜芦醇最佳提取工艺。结论:优选出的最佳工艺条件,经验证其结果稳定,方法可行。OBJECTIVE To optimize the extraction procedure for resveratrol of Polygonum cuspidatum. METHODS The extraction technique was designed by orthogonal design, taking resveratrol extraction rate as indicators, and exploring the in- fluence of factors such as the yield of solids extracted, extraction temperature, extraction time and so on. RESULTS The optimum condition of extraction process was that the crude herb powder was decocted in20-fold water,at temperature of 60 ℃, 12 h each time. CONCLUSION The repeated experimental results are stable, and the method is feasible.

关 键 词：虎杖 白藜芦醇 正交试验 提取工艺 

分 类 号：R943[医药卫生—药剂学]