手足口病患儿心肌肌钙蛋白I、CK-MB检测的临床意义  

CLINICAL SIGNIFICANCE OF DETECTING CARDIAC TROPONIN I AND CK-MB IN CHILDREN WITH HAND-FOOT-AND-MOUTH DISEASE

作　　者：彭建霞[1] 何亚萍[1] 武国霞[1] 张双[1] 

机构地区：[1]河北省唐山市妇幼保健院儿内科急诊,唐山063000

出　　处：《现代预防医学》2011年第2期249-250,共2页Modern Preventive Medicine

基　　金：唐山市科技局市级科研项目(09130202A-3-36)

摘　　要：[目的]探讨血清心肌肌钙蛋白I(cTnI)、肌酸激酶同工酶(CK-MB)检测对于手足口病合并心肌损害的临床意义。[方法]检测276例手足口病患儿血清cTnI、CK-MB水平,同时选择60例健康查体小儿作为对照组。[结果]手足口病患儿血清cTnI和CK-MB水平明显高于对照组(P﹤0.01);cTnI在诊断手足口病合并心肌炎的敏感度高于CK-MB;cTnI窗口时间明显高于CK-MB。[结论]手足口病患儿易合并心肌损害、心肌炎。血清cTnI、CK-MB对早期诊断手足口病心肌损害、心肌炎有重要意义,且cTnI测定在诊断手足口病合并心肌炎的价值更大。[Objective]To investigate the clinical significance of detecting cardiac troponin I and CK-MB in children with hand-foot-and-mouth disease and myocardial injury.[Methods]276 children with hand-foot-and-mouth disease were detected the level of serum cTnI and CK-MB.At the same time,60 cases healthy children were chosen as control group.[Results]The level of serum cTnI and CK-MB in the sick children with HFMD were significantly higher than the control group（p﹤0.01）.cTnI was more sensitive than CK-MB in the diagnosis of HFMD.The window time of cTnI was significantly higher than CK-MB.[Conclusion]Sick children with HFMD were prone to occur myocardial injury and myocarditis.Serum cTnI,CK-MB had important significance in early diagnosing HFMD with myocardial injury and myocarditis,and cTnI was more worthy of diagnosing HFMD with myocarditis.

关 键 词：手足口病 心肌损伤 心肌肌钙蛋白I 肌酸激酶同工酶 

分 类 号：R115[医药卫生—公共卫生与预防医学]