花式280与宫铜300宫内节育器临床效果比较  

Clinical study of HCu280 and Cu300 intrauterine devices

作　　者：周妍 吕阳 张文辉 杜蔚云 马旭红 王月霞 史瑞霞 马瑞兰 晋海红 刘欣辉 

机构地区：[1]甘肃省计划生育科学技术研究所,甘肃兰州730000

出　　处：《中国实用妇科与产科杂志》2011年第2期137-140,共4页Chinese Journal of Practical Gynecology and Obstetrics

基　　金：国家科技支撑计划课题(编号2006BAI15B02)

摘　　要：目的探讨花式280与宫铜300两种宫内节育器(IUD)规范应用1年的临床效果、可行性和可接受性。方法采用前瞻性研究方法,自2007年7月1日至2008年12月30日,在甘肃农村已婚育龄妇女中随机放置花式280与宫铜300各1070例,共2140例,1年末的随访率为100.00%。结果使用满12个月时,花式280和宫铜300的累积续用率分别为97.57/100妇女和97.66/100妇女,累计妊娠率分别为0.19/100妇女和0.47/100妇女,累计脱落和下移率分别为1.51/100妇女和1.69/100妇女,累计终止率分别为2.43/100妇女和2.34/100妇女,累计因症终止率分别为0.65/100妇女和0.37/100妇女。最常见的副反应为出血和疼痛。结论规范应用花式280与宫铜300可有效提高避孕方法的使用效果,两种IUD避孕效果好,值得进一步推广应用。Objective To observe the contraceptive effectiveness, feasibility and acceptability of two kinds of copper intrauterine device（HCu280 and GT300） in one year. Methods Clinical data were analyzed with prospective randomized study ,2140 Gansu rural married women of child-bearing age were brought into this study between July 1 of 2007 and Dec. 31 of 2008 ,HCu280 and GT300 each place 1070 cases. And the follow-up rate of one-year later was 100. 00%. Results the cumulative continuation rates in the 12 months for HCu280 and GT300 were 97.57 per 100 women and 97.66 per 100 women, the cumulative pregnancy rates were 0. 19 per 100 women and 0. 47 per 100 women, the expulsion or moves rate were 1.51 per 100 women and 1.69 per 100 women,the cumulative discontinuation rate were 2.43 per 100 women and 2. 34 per 100 women,the cumulative rates of removal for the side reaction were 0. 65 per 100 women and 0. 37 per 100 women,bleeding and ache was the most common adverse event. Conclusions Standard application HCu280 and GT300 can effectively improve the use of contraceptives. HCu280 and GT300 are effective for contraception. They are worthy of wide spreading in rural areas.

关 键 词：宫内节育器 避孕 可接受性 续用率 终止率 副反应 

分 类 号：R71[医药卫生—妇产科学]