一种包夹硅球型大内径毛细管整体柱的制备及评价  

A Silica-Microspheres-Entrapped Monolithic Column Prepared in situ in a Capillary of a Large Internal Diameter

作　　者：李金祥[1] 付晓伟[1] 韩晶[1] 

机构地区：[1]辽宁师范大学化学化工学院,辽宁大连116029

出　　处：《鲁东大学学报（自然科学版）》2011年第1期41-43,75,共4页Journal of Ludong University:Natural Science Edition

基　　金：辽宁省自然科学基金(2050815)

摘　　要：在内径为530μm石英毛细管中原位制备了一种包夹硅胶微球型有机整体柱,并对所制备毛细管整体柱固定相的微观结构、抗压性、溶胀性和柱效等性能因素进行了评价.结果表明,该整体柱不仅硅球分布均匀,孔径分布范围窄,耐压性强,柱效高,液相传质速度快,而且具有极强的抗溶胀能力.A silica-microspheres-entrapped monolith was in situ prepared in a 530 μm i.d.fused silica capillary.Performance factors of the prepared monolith capillary column including microstructure,resisting pression ability,permeability,anti-swelling and column efficiency were evaluated.The results show that the monolith is not only homogeneous in the distribution of the entrapped microspheres,narrower in the distribution of pore sizes,faster in mass-transfer,and higher in column efficiency,but also more stable in mechanical strength and stronger in anti-swelling in a mobile phase of a high ACN concentration.

关 键 词：色谱 整体柱 溶胀性 

分 类 号：O657.8[理学—分析化学]