新生儿缺氧缺血性脑病(HIE)的CT表现与临床疗效关系的评估  

Evaluation of the relationship between CT appearance and clinical treatment effect of HIE in neonate

作　　者：王颖 崔其亮 肖有成 江魁明 冯志明 江素霞 

机构地区：[1]广州市第二人民医院放射科,510150 [2]广州市第二人民医院新生儿科,510150

出　　处：《影像诊断与介入放射学》1999年第3期136-138,共3页Diagnostic Imaging & Interventional Radiology

基　　金：广东省科委资助项目;课题号:[1996]105号

摘　　要：目的:评估新生儿缺氧缺血性脑病(HIE)CT表现与临床疗效。材料与方法:通过对97例新生儿HIE低密度灶不同脑叶分布及其CT值变化并结合其中46例不同时期随访表现进行分折。结果:97例新生儿HIE分布于不同脑叶的低密度灶共301个,其CT值在25Hu-12Hu之间,与非病变区脑组织密度及对照组的正常脑组织密度具有显著性差异(P<0.05)。本组资料显示HIE低密度灶明显集中于额叶及颞叶;枕叶及顶叶较少。46例不同时期随访的CT检查显示位于颈叶、颈叶较小病灶吸收恢复时间明显早于枕叶及顶叶,其中较大面积的低密度灶恢复时间要长且有可能形成更低密度的脑软化灶(CT值<15Hu)。结论:新生儿HIE低密度灶出现于顶叶或枕叶其恢复时间要长于颞叶及额叶,较大面积的低密度灶(10mm-15mm)有可能形成脑软化灶并导致相应的临床症状出现。Purpose: Evaluating the relationship between the brain tissue edemic lower density foci distributed differencial cerebral lobe due to hypoxia ischemic encephalopathy (HIE) of neonate and the clinical prognosis. Meterials and methods: Distributed differencial cerebral lobe lower density foci appearing in HIE 97 cases and combinated with followed-up survey 46 cases during one month, inner or over six months in this series. Resuhu: Sum total three hundred and one foci seen in various cerebral lobe of which CT value was between 25Hu - 12Hu, and compared with non-lesion area or contasting group, there were markedly difference (P<0.05). The foci much more seen in FL(108) and TL(89), rarely PL(32) The recovering period, in generally, foci located FL, TL Would be taken lesser time than OL and PL. Larger focus, meanwhile, may be forming cerebromalacia that CT value < 15Hu. Conclusion: To analyze CT manifestation that manifested variouo period might be useful for evaluating the clinical prognosis of HIE.

关 键 词：新生儿 缺氧缺血性脑病 低密度灶 预后 CT 疗效 

分 类 号：R722.12[医药卫生—儿科]