Tetrahymena Gene Expression Database (TGED):A resource of microarray data and co-expression analyses for Tetrahymena  

作　　者：XIONG Jie LU XingYi LU YuMing ZENG HongHui YUAN DongXia FENG LiFang CHANG Yue Josephine BOWEN Martin GOROVSKY FU ChengJie MIAO Wei 

机构地区：[1]Key Laboratory of Aquatic Biodiversity and Conservation, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, China [2]State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, China [3]Department of Biology, University of Rochester, Rochester, NY 14627, USA [4]Graduate University of Chinese Academy of Sciences, Beijing 100049, China

出　　处：《Science China(Life Sciences)》2011年第1期65-67,共3页中国科学（生命科学英文版）

基　　金：supported by the National Natural Science Foundation of China (Grant Nos. 30870356 and 30970424);the Knowledge Innovation Program of Chinese Academy of Sciences (Grant No. KSCX2-YW-G-072);the National Institutes of Health (Grant Nos. GM021793 and GM072752)

摘　　要：Tetrahymena thermophila is a model eukaryotic organism. Functional genomic analyses in Tetrahymena present rich opportunities to address fundamental questions of cell and molecular biology. The Tetrahymena Gene Expression Database (TGED; available at http://tged.ihb.ac.cn) is the first expression database of a ciliated protozoan. It covers three major physiological and developmental states: growth, starvation, and conjugation, and can be accessed through a user-friendly web interface. The gene expression profiles and candidate co-expressed genes for each gene can be retrieved using Gene ID or Gene description searches. Descriptions of standardized methods of sample preparation and the opportunity to add new Tetrahymena microarray data will be of great interest to the Tetrahymena research community. TGED is intended to be a resource for all members of the scientific research community who are interested in Tetrahymena and other ciliates.Tetrahymena thermophila is a model eukaryotic organism. Functional genomic analyses in Tetrahymena present rich opportunities to address fundamental questions of cell and molecular biology. The Tetrahymena Gene Expression Database （TGED; available at http：//tged.ihb.ac.cn） is the first expression database of a ciliated protozoan. It covers three major physiological and developmental states： growth, starvation, and conjugation, and can be accessed through a user-friendly web interface. The gene expression profiles and candidate co-expressed genes for each gene can be retrieved using Gene ID or Gene description searches. Descriptions of standardized methods of sample preparation and the opportunity to add new Tetrahymena microarray data will be of great interest to the Tetrahymena research community. TGED is intended to be a resource for all members of the scientific research community who are interested in Tetrahymena and other ciliates.

关 键 词：Tetrahymena thermophila gene expression database CO-EXPRESSION 

分 类 号：Q959.116[生物学—动物学] Q78