氯硝西泮合并帕罗西汀治疗酒依赖伴抑郁的临床分析  

Clinical analysis of clonazepam combined paroxetine in treatment of alcohol dependence and depression

作　　者：卢智慧[1] 

机构地区：[1]云南省红河州第二人民医院,云南建水654300

出　　处：《中国当代医药》2011年第3期52-53,共2页China Modern Medicine

摘　　要：目的：观察氯硝西泮合并帕罗西汀治疗酒依赖伴抑郁的疗效。方法：本组20例患者入院即采用氯硝西泮合并帕罗西汀治疗,氯硝西泮2~6mg/d,分2~4次肌注;帕罗西汀20~40mg/d,早上7：00一次性服用。结果：20例患者中,生理依赖症状完全消除18例,好转2例;心理依赖症状好转16例。抑郁症状完全消除10例,进步6例,有效2例,无效2例,总有效率为90%。结论：氯硝西泮合并帕罗西汀治疗酒依赖伴抑郁疗效显著,戒断症状少,安全性高。Objective：To observe the effect of the treatment of alcohol dependence and depression with clonazepam as well as paroxetine.Methods：Slected 20 patients with clonazepam and paroxetine treatment,2-6 mg/d of clonazepam was offered to the patients by intramuscular injection for 2-4 times a day.And 20-40 mg/d of paroxetine was taken at 7：00 pm for only once a day.Results：In 20 patients,18 cases physiological dependence totally eliminated and 2 cases improved,16 cases psychological dependence improved.10 cases of depression totally eliminated,6 cases progressed,2 cases was ef fective and 2 cases had no efficacy.Conclusion：The treatment,in which clonazepam and paroxetine are used to treat alcohol dependence and depression,is striking.It is safe with little withdrawal syndrome.

关 键 词：氯硝西泮 帕罗西汀 酒依赖 抑郁 

分 类 号：R971[医药卫生—药品]