小儿迁延性腹泻与锌缺乏病发病关系研究  

Relationship of Persistent Diarrhea to Zinc Deficiency in Children

作　　者：王冬萌[1] 毕晶[1] 孙正纤[1] 

机构地区：[1]河北省保定市儿童医院内四科,071051

出　　处：《中国全科医学》2011年第2期196-197,共2页Chinese General Practice

摘　　要：目的探讨小儿迁延性腹泻与锌缺乏病之间的关系。方法选取2007—2009年217例迁延性腹泻患儿、176例锌缺乏病患儿及182例健康儿童。对比其血锌水平及年腹泻发病次数。结果迁延性腹泻组血锌水平(53.36±10.64)μmol/L,明显低于对照组的(76.20±11.24)μmol/L,差异有统计学意义(t=18.40,P<0.05)。锌缺乏病组年腹泻发病次数为(3.53±1.72)次/年,明显高于对照组的(1.90±0.93)次/年,差异有统计学意义(t=5.26,P<0.05)。结论迁延性腹泻导致锌吸收障碍,锌缺乏造成消化能力下降、免疫功能障碍,两者互为因果,造成恶性循环。Objective To explore the relationship between persistent diarrhea（PD） and zinc deficiency（ZD） in children.Methods Two hundred seventeen PD（PD group）,176 ZD（ZD group）and 182 healthy children（control group） were enrolled from the year of 2007 to 2009.Serum zinc levels and diarrhea frequencies were compared.Results Serum zinc level was significantly lower in PD group [（53.36±10.64）μmol/L] than in control group [（76.20±11.24）μmol/L]（t=18.40,P〈0.05）;diarrhea frequency higher in ZD group [（3.53±1.72）times/year] than in control group [（1.90±0.93）times/year]（t=5.26,P〈0.05）.Conclusion PD leads to zinc malabsorption and ZD to decreased digestion,immune dysfunction,which interact each other and creat a vicious circle.

关 键 词：腹泻 儿童 锌 发病率 

分 类 号：R723.11[医药卫生—儿科]