我国不同人群输血传播病毒感染调查  

Detection of transfusion transmitted virus (TTV) in different populations of China

作　　者：凌斌华[1] 庄辉[1] 李奎[1] 杨永芳[2] 李盛[3] 马为民[4] 王跃民 

机构地区：[1]北京医科大学微生物学系,100083 [2]云南省卫生防疫站 [3]安徽医科大学 [4]深圳市东湖医院 [5]青岛市疾病控制中心

出　　处：《中华流行病学杂志》1999年第5期277-279,共3页Chinese Journal of Epidemiology

摘　　要：目的　了解不同人群输血传播病毒 (TTV)的感染状况。方法　采用套式PCR法检测血清标本中TTVDNA ,并对其中 1株TTV的部分基因序列进行了测定。结果　不同人群TTVDNA阳性率分别为 :正常体检人群 10 .3% ,献血员 43.7% ,吸毒者 15 .6% ,血液透析病人5 4.4% ,妓女 65 .0 % ,慢性丙型肝炎病人 2 5 .0 % ,非甲～庚型肝炎 0 / 11。Objective To investigate the prevalence of transfusion transmitted virus (TTV) in different populations of China. Methods TTV DNA was detected in sera collected from different populations by nested PCR. Partial gene of a TTV isolate was directly sequenced. Results The prevalences of TTV in various populations were as follows: 10.3 % (31/301) in general population when receiving physical checkup; 43.7 % (14/32) in blood donors; 15.6 % (5/32) in intravenous drug addicts; 54.4 % (6/11) in hemodialysis patients; 65% (13/32) in prostitutes; 25% (4/16) in patients with chronic hepatitis C. None of the 11 patients with non A-G hepatitis was detected TTV DNA. Conclusion High prevalence of TTV infection was found in different populations of China.

关 键 词：输血传播病毒 聚合酶链反应 肝炎病毒 流行病学 

分 类 号：R512.601[医药卫生—内科学]