老年人药品不良反应分析  

Analysis of Adverse Drug Reactions in Elderly Patients

作　　者：王雪梅[1] 王思媛[1,2] 沈芊[1] 

机构地区：[1]首都医科大学宣武医院药剂科,北京100053 [2]北京卫生学校,药学专业北京100053

出　　处：《中国医院用药评价与分析》2010年第12期1114-1117,共4页Evaluation and Analysis of Drug-use in Hospitals of China

摘　　要：目的:了解老年人服用药物出现的不良反应。方法:采用回顾性的调查方法,对首都医科大学宣武医院2005—2008年所收集的933份老年人用药不良反应进行数据分析。结果:在统计的这933份不良反应报表中,男性406例,女性527例,平均年龄71.73岁;涉及药物245种,主要为中成药269例(28.83%),其次为抗感染及抗病毒药227例(24.33%);不良反应的主要表现是皮肤及其附件损害,其次是中枢神经系统症状;用药途径主要为静脉滴注和口服。结论:重视和加强老年人用药不良反应的监测工作,以保证用药的安全性。OBJECTIVE：To probe into the adverse drug reactions（ADR） occurred in elderly patients.METHODS： By a retrospective review,the data of 933 ADR case reports collected in Xuanwu Hospital of Capital Medical University from 2005 to 2008 were analyzed.RESULTS： Of the 933 ADR cases reviewed,406 were males and 527 females with a mean age of 71.73 years.245 drugs were involved in the ADR cases,predominantly the traditional Chinese medicines which caused ADR in 269 cases（28.83%）,followed by anti-infective and antiviral drugs in 227 cases（24.33%）.The chief manifestations of the ADR were lesion of skin and its appendants,followed by symptoms of central nervous system.The chief routes of administration included intravenous drip and oral administration.CONCLUSION： It is important to attach importance to strengthen ADR monitoring in elderly patients to ensure their medication safety.

关 键 词：老年人 药品不良反应 分析 

分 类 号：R969.3[医药卫生—药理学]