急性弥漫性颅脑损伤与局灶性颅脑损伤的比较研究  

The comparison between acute diffuse craniocerebral injury and local craniocerebral injury

作　　者：徐育林 杨新宇[2] 杨树源 王明璐 

机构地区：[1]广西桂林市第二人民医院 [2]天津医科大学总医院

出　　处：《医学文选》1999年第1期6-8,共3页Anthology of Medicine

摘　　要：目的比较急性弥漫性颅脑损伤与局灶性颅脑损伤在脑组织破坏以及其它脏器反应上的差别。方法对非火器性急性闭合性颅脑损伤病人进行ＣＳＦ中髓鞘碱蛋白（ＭＢＰ）检测，肝、肾功能检查，血糖、电解质测定，血气分析，并行临床ＧＣＳ评分和伤后６个月ＧＯＳ评定。结果弥漫性颅脑损伤组ＣＳＦＭＢＰ、血糖明显高于局灶性组，而ＧＯＳ评分、血氧分压明显低于局灶性组。不同预后患者入院时ＣＳＦＭＢＰ水平显著不同，预后越差，ＣＳＦＭＢＰ水平越高。ＣＳＦＭＢＰ与血糖、血氧分压均有相关性。结论综合分析ＣＳＦＭＢＰ、血糖。Objective \ To recognire the difference of brain damage and the reation of other organs between the actue diffuse craniocerebral injury(DCI) and local craniocerebral injury(LCT) Methods \ The CSF myelin basic protein(MBP), the function of liver and kidney the blood glucose K+Na+Cl-,and blood gas were measured in acute craniocerebral injury patient, and the GCS was graded after admission After 6 moths, the GOS was assessed Results The CSF-MBP blood glucose were significantly higher in the DCI group than in the LCT group But the GOS, PO2 were significantly lower in the DCI group than in the LCT one The higher CSF-MBP, the worse the prognosis is The CSF-MBP level was correlated to the blood glucose and PO2 Conclusions The prognosis of the DCI was correctly assessed by measuring CSF-MBP, blood glucose, PO2 and the GCS grade

关 键 词：弥漫性 颅脑损伤 局灶性 髓鞘碱蛋白 血糖 

分 类 号：R651.15[医药卫生—外科学]