黄芪注射液对慢性心力衰竭急性失代偿患者中医症状和证型的影响  

Effect of Astragalus Injection on Traditional Chinese Medical Symptoms and Syndrome Patterns of Acute Decompensated Chronic Heart Failure Patients

作　　者：徐慧聪[1] 宋光辉[1] 沈嫱[1] 孙鹏涛[1] 石小红[1] 覃勇[1] 

机构地区：[1]广东省中医院二沙急诊科,广东广州510105

出　　处：《新中医》2011年第2期22-24,共3页New Chinese Medicine

基　　金：广州中医药大学创新基金资助项目(编号:K0070065)

摘　　要：目的:探讨黄芪注射液对慢性心力衰竭急性失代偿(ADCHF)患者中医症状及证型的影响。方法:将118例ADCHF患者随机分为试验组60例,对照组58例。试验组予以黄芪注射液结合西医常规治疗,对照组予以西医常规治疗。用药7天后观察2组中医症状发生情况与中医证型情况的变化。结果:2组用药后呼吸困难程度比较,差异有显著性意义(P<0.05),用药后试验组呼吸困难程度轻于对照组。用药后,2组心悸发生情况比较,差异有显著性意义(P<0.05),试验组优于对照组。2组治疗前及用药后各中医证型情况比较,差异均无显著性意义(P>0.05)。2组治疗前与用药后气阴两虚证无变化,气虚证和气阳虚证有变化。试验组有12例(20.0%)证型发生变化,7例(11.7%)为气虚证转变为气阴两虚证,5例(8.3%)为气阳虚证转变为气虚证。对照组有17例(29.3%)证型发生变化,13例(22.4%)为气虚证转变为气阴两虚证,4例(6.9%)为气阳虚证转变为气虚证。结论:黄芪注射液可改善ADCHF患者的呼吸困难、心悸等症状,并可使ADCHF患者的阳虚表现得到改善甚至完全缓解,转变为气虚。Objective： To observe the effect of Astragalus Injection（AI）on traditional Chinese medical （TCM） symptoms and syndrome patterns of acute decompensated chronic heart failure（ADCHF）patients. Methods： One hundred and eighteen ADCHF patients with qi deficiency were randomly divided into two groups. The control group （n=58） received routine western medical treatment, and the treatment group （n=60） received routine western medical treatment combined with AI. The changes of symptoms and syndrome patterns were observed after 7 days. Results： Dyspnea was much relieved and the incidence of palpitation was decreased in the treatment group after treatment （P 〈 0.05 compared with the control group）. No significant difference was found in the distribution of syndrome patterns between two groups before and after treatment （P 〉 0.05）. After treatment, 7（11.7%） patients with the syndrome of qi deficiency were transformed into deficiency of both qi and yin, and 5 （8.3%）with deficiency of both qi and yang transformed into qi deficiency in the treatment group. In the control group, 13（22.4%） patients with the syndrome of qi deficiency were transformed into deficiency of both qi and yin, and 4（6.9%）with deficiency of both qi and yang transformed into qi deficiency. Conclusion. AI can relieve symptoms such as dyspnea and cardiopalmus in ADCHF patients, improve syndrome of yang deficiency or even transform yang deficiency into qi deficiency.

关 键 词：慢性心力衰竭 失代偿 中医疗法 黄芪注射液 中医症状 中医证型 

分 类 号：R541.6[医药卫生—心血管疾病]