拟除虫菊酯农药的结构效应分析及QSAR研究  

The Analysis of Structure Effect and Research on QSAR of the Pyrethroid Insecticides

作　　者：李玲玉[1,2] 颜冬云[1,2] 王春光[1] 秦文秀[1] 

机构地区：[1]青岛大学化学化工与环境学院,山东青岛266071 [2]中国科学院南京土壤研究所土壤与农业可持续发展国家重点实验室,南京210008

出　　处：《农药》2011年第2期83-86,118,共5页Agrochemicals

基　　金：土壤与农业可持续发展国家重点实验室开放基金(Y052010023)

摘　　要：拟除虫菊酯类农药的广泛应用引起了全社会对农药安全问题的关注,很大程度上刺激了最大限度地发挥拟除虫菊酯类农药的使用效率和新型拟除虫菊酯类农药的开发。人们越来越认识到保持拟除虫菊酯的高效性与持续攀升的使用量将需要更多地探究其结构-活性效应。综述了不同结构拟除虫菊酯及其异构体的活性/性质差异以及国内外拟除虫菊酯类农药的QSAR研究进展,并对拟除虫菊酯QSAR研究进行了展望,可为新型高效低毒农药的研发提供理论支撑。the increasing societal concern about the safety of pesticide caused by the worldwide use of pyrethroid is now providing strong drivers towards maximising the efficiency of pyredthroid utilisation and the development of new pyrethroids.There is growing recognition that the ultimate goal of achieving efcient and sustainable pyrethroid usage will require greater understanding of its structure-activity relationships.The paper summarized the difference of pyrethroid isomers in the activity/property,and presented the research progress and prospect on QSAR of the pyrethroid insecticides.This article would offer theoretical basis for the study of new pesticides with high efficiency and low toxicity.

关 键 词：农药 拟除虫菊酯 结构效应 QSAR 

分 类 号：TQ450.1[化学工程—农药化工]