心肌矢量应变和应变率成像技术对晚期肝硬化患者左心室局部收缩功能的评价  

Assessment of regional left ventricular systolic function of patients with late-stage liver cirrhosis by VSI

作　　者：赵玥[1,2] 王润兰[3] 梅丽[2] 杨晓英[2] 

机构地区：[1]吉林医药学院附属医院超声科,吉林吉林132013 [2]吉林大学第一医院联合超声科,吉林长春130021 [3]吉林大学第一医院心内超声科,吉林长春130021

出　　处：《吉林大学学报（医学版）》2011年第1期150-153,197,共4页Journal of Jilin University：Medicine Edition

基　　金：吉林省科技厅科研基金资助课题(20050409-1)

摘　　要：目的:应用心肌矢量应变和应变率成像技术(VSI)观察晚期肝硬化患者左心室局部收缩功能,探讨晚期肝硬化患者左心室局部收缩功能的改变。方法:VSI技术检测30例晚期肝硬化患者(患者组)及30例年龄匹配的正常对照者(对照组)左心室16节段室壁收缩期纵向、径向应变率及圆周方向运动速度。结果:患者组纵向应变率收缩期峰值(L-SRs)前间隔中间段、前壁心尖段、室间隔心尖段较对照组减低(P<0.05);患者组径向应变率收缩期峰值(R-SRs)值前间隔中间段、室间隔心尖段较对照组减低(P<0.05);患者组圆周方向运动速度收缩期峰值(C-Vs)前壁中间段、前间隔中间段较对照组减低(P<0.05)。结论:晚期肝硬化患者在左心室整体收缩功能未受到明显影响以前,局部心肌已经出现收缩功能减低。Objective To evaluate the regional left ventricular systolic function of patients with late-stage liver cirrhosis by application of vector myocardial strain and strain rate imaging（VSI）,and discuss the changes of the regional left ventricular systolic function of patients with late-stage liver cirrhosis.Methods The longitudinal peak systolic strain rates（L-SRs）,radial peak systolic strain rates（R-SRs） and circumferential peak systolic velocity（C-Vs） in 30 patients with late-stage liver cirrhosis（patient group） and 30 cases of age-matched normal persons（control group） were detected by VSI technology.Results The L-SRs of mid-anteroseptal,apical-anterior and apical-septal in patient group were reduced compared with control group（P0.05）;the R-SRs of mid-anteroseptal,apical-anterior and apical-septal in patient group were reduced compared with control group（P0.05）;the C-Vs of mid-anterior and mid-anteroseptal in the cirrhosis group was reduced compared with control group（P0.05）.Conclusion The regional left ventricular systolic function of patients with late-stage liver cirrhosis has already reduced before the global left ventricular systolic function has not significantly affected.

关 键 词：心室功能 左 心肌矢量应变 肝硬化 功能评价 

分 类 号：R445.1[医药卫生—影像医学与核医学] R657.31[医药卫生—诊断学]