辽宁地区531例寻常性银屑病患者临床流行病学调查  

Clinical epidemiological study of 531 cases of psoriasis vulgaris in Liaoning region

作　　者：魏瑾[1] 刘梅[1] 曲乐[1] 肖汀[1] 陈洪铎[1] 何春涤[1] 

机构地区：[1]中国医科大学附属第一医院皮肤科,沈阳110001

出　　处：《国际皮肤性病学杂志》2011年第1期4-6,共3页International Journal of Dermatology and Venereology

基　　金：基金项目：辽宁省教育厅创新团队项目计划（2008T193）;教育部高等学校博士学科点专项科研基金（20092104110003）;教育部创新团队基金（IRT0760）

摘　　要：目的探讨寻常性银屑病的临床流行病学特征。方法采用统一设计的临床流行病学调查问卷，应用EpiData3．1和SPSS13．0程序软件进行数据处理与分析。结果531例寻常性银屑病患者中男女比例为1．31：1；患者的平均首次发病年龄为（25．7±13．1）岁；皮损表现以点滴状银屑病居多（49．5％），发病部位以下肢为首；有家族史者发病年龄早于无家族史者（P〈0．05）；病情加重季节主要为春季和冬季。结论寻常性银屑病的发生无性别差异，环境与遗传因素在寻常性银屑病的发生、发展中起重要作用。Objective To describe the clinical and epidemiological characteristics of psoriasis vulgaris in Liaoning region. Methods Five hundred and thirty-one outpatients with psoriasis vulgaris were surveyed by using a consensusly-designed questionnaire. EpiData3.1 and SPSS13.0 statistical softwares were used for data analysis. Results In the 531 patients with psoriasis vulgaris, the male to female ratio was 1.31 ： 1, and the average age at the first onset was 25.7± 13.1 years. Guttate lesions were the commonest clinical manifestation, and observed in 49.5% of these patients. Lower limbs seemed to be the predilection site. The age at onset was younger in patients with family history than in those without （22.5 - 12.6 years vs. 26.9 ± 13.2 years, t=3.437, P〈 0.05）. The exacerbation of psoriasis vulgaris often occurred in winter or spring. Conclusions There seems no gender difference in the development of psoriasis vulgaris, environmental and genetic factors appear to play an important role in the initiation and development of psoriasis vulgaris.

关 键 词：银屑病 流行病学 数据收集 

分 类 号：R758.63[医药卫生—皮肤病学与性病学]