探讨血管指数在慢性肾脏病诊断中的意义  

Discuss the value of vascular index in the diagnosis of chronic kidney diseases

作　　者：吴迪[1] 吕沐天[2] 王学梅[1] 刘艳君[1] 宛伟娜[1] 冯跃琴[1] 

机构地区：[1]中国医科大学附属第一医院超声诊断科,辽宁沈阳110001 [2]中国医科大学,95期1班辽宁沈阳110001

出　　处：《中国临床医学影像杂志》2011年第1期20-22,共3页Journal of China Clinic Medical Imaging

基　　金：辽宁省教育厅2006-2007年度高等学校科研项目(编号:20060970)

摘　　要：目的:探讨三维能量多普勒(3D-CPA)超声参数血管指数(Ⅵ)评估慢性肾脏病(CKD)患者肾损害的能力。方法:对60例临床诊断CKD的患者进行3D-CPA检查及肾脏组织病理活检,计算Ⅵ值及病理学积分,正常对照组30例。超声测量结果与肾穿刺活检病理结果、临床CKD分期对照分析。结果:不同病理类型的慢性肾脏疾病有不同的Ⅵ值;32例病变局限在肾小球(Ⅰ组),Ⅵ值37.64%±9.97%与对照组Ⅵ值33.44%±4.31%相接近(P≥0.05),28例病变累及肾小管间质及血管(Ⅱ组),Ⅵ值23.34%±12.12%小于I组和对照组(P<0.05);同时Ⅵ与CKD临床分期呈正相关。结论:Ⅵ可以在一定程度上反映慢性肾脏病的病理类型;病例组在Ⅵ值正常时,其病变主要累及肾小球;在Ⅵ值降低时,其病变已累及肾小管间质或血管;Ⅵ值越小,CKD临床分期越高。Objective：To explore the reliability of three-dimensional color power angiography（3D-CPA） ultrasound parameter vascular index（VI） to assess the degree of renal damage of chronic kidney disease（CKD）.Methods：Sixty patients suspected with chronic kidney disease underwent 3D-CPA and percutaneous biopsy,and 30 healthy adults served as control.The VI and pathological change scoring of renal were measured,and the correlation of VI and pathological findings as well as clasification of CKD were analyzed.Results：Different types of renal diseases had different VI;Thirty-three patients in the group I,the diseases limited to the glomeruli,VI（37.64%±9.97%） was closed to that of the control group（33.44%±4.31%）（P≥0.05）.Twenty-eight patients in group II,the diseases positioned in the tubulo-interstitial and blood vessel,VI（23.34%±12.12%） was higher than that of group I and the control group（P0.05）.There was a significant correlation between the value of VI and classification of CKD.Conclusions：VI can reflect the types of renal diseases.In case of CKD with VI in normal limit,the diseases may be limited to the glomeruli;while the VI elevated,the diseases may locate in the tubulo-interstitial or blood vessel;The lower the VI,the higher the classification of CKD.

关 键 词：肾疾病 超声检查 多普勒 彩色 

分 类 号：R692[医药卫生—泌尿科学] R445.1[医药卫生—外科学]