老年患者革兰阴性杆菌肺炎的主要病原菌耐药性调查  

Drug resistance of gram-negative bacilli causing pneumonia in senile patients

作　　者：尧兴水 

机构地区：[1]湖北省崇阳县人民医院检验科,湖北崇阳县437500

出　　处：《中华医院感染学杂志》2011年第3期585-586,共2页Chinese Journal of Nosocomiology

摘　　要：目的调查老年患者革兰阴性杆菌肺炎的病原菌分布及耐药状况,为临床预防感染及合理使用抗菌药物提供试验依据。方法细菌培养鉴定按照《全国临床检验操作规程》进行;药物敏感试验采用K-B法。结果 172株老年患者肺炎的主要革兰阴性杆菌为铜绿假单胞菌(29.7%)、肺炎克雷伯菌(27.3%)、大肠埃希菌(22.1%)、阴沟肠杆菌(11.6%),以上细菌对常用抗菌药物均产生了不同程度的耐药性,但对亚胺培南、美罗培南100.0%敏感。结论老年患者革兰阴性杆菌肺炎的病原菌耐药性呈上升趋势,应采取综合性预防与控制措施。OBJECTIVE To investigate the pathogenic distribution and drug resistance of Gram-negative bacilli causing pneumonia in senile patients and provide the scientific evidence for clinical prevention of infection and use of antibiotics.METHODS Referring to Rules of Operation in Clinical Laboratory of Nationwide,the strains were cultured and identified.The antibiotic susceptibility testing was performed by K-B method.RESULTS Among 172 strains of Gram-negative bacilli,the top 4 of isolating rate were Pseudomonas aeruginosa（29.7%）,K.pneunmoniae（27.3%）,Escherichia coli（22.1%） and Enterobacter cloacae（11.6%）.The drug-resistance of above strains had been resistant to commonly used antibiotics in different degree.The rate of susceptibility of imipenem and meropenem was all 100.0%.CONCLUSION The drug resistance of Gram-negative bacilli causing pneumonia in senile patients keeps an upward tendency.The comprehensive prevention and control measures should be adopted.

关 键 词：老年患者 肺炎 革兰阴性杆菌 耐药性 

分 类 号：R378[医药卫生—病原生物学]