超声波辐射下相转移催化法合成苯并噻唑基硫代羧酸  

Synthesis of the Benzothiazolylthio Carboxylic Acids by Use of Ultrasound Irradiation in Phase Transfer Catalysis Medium

作　　者：李英俊[1] 李丽娜[1] 孙淑琴[1] 胡志君[1] 宋永波[1] 

机构地区：[1]辽宁师范大学化学化工学院,辽宁大连116029

出　　处：《河北师范大学学报（自然科学版）》2011年第1期63-65,共3页Journal of Hebei Normal University：Natural Science

基　　金：辽宁省自然科学基金(20102126);辽宁省教育厅高等学校科研基金(2008345)

摘　　要：报道了采用超声波辐射与相转移催化联用技术合成苯并噻唑基硫代乙酸和丙酸,并经IR,1HNMR和13CNMR确定了其结构.探索了反应温度、时间、溶剂、催化剂及超声波对这类化合物合成反应的影响,确定了最佳合成条件.与文献法相比,该方法具有反应条件温和、操作简便、反应时间短、反应温度低、产率高等优点.Benzothiazolylthio carboxylic acids,（2-benzothiazolylthio） acetic acid and 3-（2-benzothiazolylthio）propionic acid were synthesized by the technique of ultrasonic irradiation and phase transfer catalysis.Their structures were confirmed by IR,1HNMR and13CNMR.The influences of the reaction temperature,the reaction time,the solvent,the catalyst and the ultrasonic irradiation on the reaction were investigated and optimum experimental conditions were found.Compared with the literature methods,this synthetic method had such advantages as mild condition,simple operation,short reaction time,lower reaction temperature and higher yield.

关 键 词：苯并噻唑基硫代羧酸 合成 超声波辐射 相转移催化 

分 类 号：O622.3[理学—有机化学]