干扰素治疗轮状病毒肠炎的疗效观察  

Efficacy Observation of Interferon Treatment for Rotavirus Enteritis

作　　者：李娟[1] 谢路[1] LI Juan,XIE Lu（Kunming Pediatrics and Child Health Hospital Yunnan Province,Kunming 650031,China）

机构地区：[1]云南省昆明市妇幼保健院儿科,云南昆明650031

出　　处：《医学信息》2011年第4期728-729,共2页Journal of Medical Information

摘　　要：目的观察干扰素治疗轮状病毒肠炎的疗效。方法将我院196例轮状病毒肠炎,随机分为治疗组及对照组,对照组给予利巴韦林、思密达及肠道益生菌,治疗组在对照组的基础上加用重组人α-1b干扰素注射液。结果经过治疗组痊愈时间平均为3.6d,显著少于对照组的平均6.8d,差异有统计学意义（P〈0.05）。结论干扰素治疗轮状病毒肠炎安全可靠、可明显缩短患儿发热、腹泻时间、减少并发症的发生,疗效显著、且副作用少,值得临床推广应用。Objective observed Interferon treatment rotavirus enteritis efficacy.Methods 196 cases of rotavirus enteritis were randomly divided into treatment group and control group in our hospital,control group patients were given ribavirin,Smecta and probiotics,Treatment group patients were given recombinant human α-1b interference injection in the control group based on.Results after treatment,the treatment group healed time was an average of 3.6 days,significantly less than the average 6.8 days in control group,the difference was statistically significant（P0.05）.Conclusion Interferon treatment rotavirus enteritis was safe,reliable,children can significantly reduce the fever,diarrhea,reduce the incidence of complications,a significant effect and less side effects,worthy of clinical application.

关 键 词：干扰素 轮状病毒肠炎 

分 类 号：R512.5[医药卫生—临床医学;医药卫生—内科学]