谷氨酰胺强化肠内营养对接受呼吸机治疗的COPD患者营养状况及呼吸功能的影响  

The impact of glutamine ennoblement enteral nutritional on nutritional status,respiratory function of COPD patients undergoing ventilator therapy

作　　者：吴晓娜[1] 腾洪[1] 崔越[1] 

机构地区：[1]四川省人民医院营养科呼吸科,四川成都610072

出　　处：《四川医学》2011年第1期47-48,共2页Sichuan Medical Journal

摘　　要：目的评价谷氨酰胺强化肠内营养对接受呼吸机治疗的COPD患者的作用。方法采用前瞻性随机对照实验设计,28例患者分为强化谷氨酰胺组(15例)和普通肠内营养组(13例)。两组患者接受等氮等热量的10d肠内营养支持,研究两种方法在血气分析、血浆蛋白等方面的不同作用。结果接受肠内营养支持10d后,两组患者血浆清蛋白结果相似(P>0.05),血浆总蛋白和前清蛋白差异有统计学意义(P<0.05),强化谷氨酰胺组促进体内蛋白合成作用强于普通肠内营养组;血气指标两组结果相似(P>0.05),但强化谷氨酰胺组略好。结论对接受呼吸机辅助呼吸,肝肾功能大致正常的COPD患者,强化G ln的肠内营养是较好的营养支持方法。Objective To evaluate the effects of glutamine ennoblement enteral nutrition on the COPD patients who were undergoing the ventilator therapy.Methods Twenty-eight cases were randomized into common enteral nutrition group（13）and glutamin ennoblement enteral nutrition group（15）.The two groups were given 10 days nutrition support of isonitrogenous and isocaloric;The different effects on blood gas indexes and protein of blood plasmas were compared.Results The two groups had the similar results in blood plasmas albumin,had significant differences in blood plasma pro-albumin and total protein（P0.05）.The similar blood gas parameters were observed in two groups,but the glutamine ennoblement group had the better parameters.Conclusion Glutamine ennoblement enteral nutrition was a better nutrition support approach for the COPD patients with normal liver and renal functions who were undergoing ventilator therapy.

关 键 词：谷氨酰胺 肠内营养 COPD 

分 类 号：R563.9[医药卫生—呼吸系统]