经尿道局部电切术加小剂量丝裂霉素膀胱灌注治疗腺性膀胱炎疗效观察(附30例报告)  

Treatment of cystitis glandularis by Transurethral resection plus local low-dose mitomycin intravesical therapy

作　　者：彭启伦[1] 张洪敏[1] 夏川[1] 杨凡[1] 潘向东[1] 彭海涛[1] 

机构地区：[1]峨眉山市人民医院泌尿外科,四川峨眉山614200

出　　处：《四川医学》2011年第1期67-68,共2页Sichuan Medical Journal

摘　　要：目的探讨腺性膀胱炎的有效诊断和治疗手段。方法对68例患者采用膀胱镜及病理检查明确诊断。随机分为A、B两组,行经尿道病部病灶电切,两组分别采用不同剂量丝裂霉素术后灌注。结果随访2～5.5年,小剂量丝裂霉素A组治愈16例,好转14例,术后复发2例,无血白细胞和肝肾毒性损害发生,大剂量丝裂霉素B组治愈15例,好转17例,术后复发4例。结论经尿道电切术加小剂量丝裂霉素膀胱腔内灌注治疗腺性膀胱炎术后治愈率、复发率与大剂量丝裂霉素比较差异无统计学意义,具有安全性高,毒性小的特点。Objective To report the diagnosis and treatment of 68 cases of cystitis glandularis.Methods Cystitis glandularis was diagnosed in 68 patients,and data were randomly divided into A,B groups.They all underwent cystoscopic examination and transurethral resection of bladder lesion,and received bladder irrigation in differrnt doses of mitomycin.Results Followed up for 2 to 5.5 years,16 patients in A group were cured,14 cases improved,2 cases of recurrence,and 15 cases of B group were cured,improved in 17 cases,4 cases of recurrecnce,no damage of liver and kidney toxicity coccurred.Conclusion There was no significant difference with postoperative cure tate,relapse rate between low-dose mitomycin bladder instillation and large-dose mitomycin bladder instillation after transurethral resection,low-dose mitomycin blader instillation have high security and low toxicity characteristics.

关 键 词：腺性膀胱炎 经尿道膀胱病变电切术 膀胱灌注 

分 类 号：R694.3[医药卫生—泌尿科学]