儿童EB病毒感染29例临床分析  

Clinical Analysis of 29 Children with Epstein-Barr Virus Infections

作　　者：白淑霞[1] 孙洁[1] 李智慧[1] 邓娜[1] 付宇[1] 丁希伟[1] 王金堂[1] 

机构地区：[1]湖北医药学院附属人民医院儿科,湖北十堰442000

出　　处：《临床误诊误治》2011年第1期24-25,共2页Clinical Misdiagnosis & Mistherapy

摘　　要：目的对儿童EB病毒（EBV）感染的临床表现、实验室检查和误诊情况进行分析,以提高EBV感染的诊断水平。方法回顾分析我院2007年1月~2009年12月用酶联免疫吸附（ELISA）法检测EBV-VCR-IgM诊断EBV感染29例的临床资料。结果 EBV感染多表现为发热、咽峡炎、淋巴结增大、肝脾大,亦可出现咳嗽、黄疸、眼睑水肿、皮疹、抽搐、消化道大出血等症状。实验室检查外周血白细胞计数增高,以淋巴细胞增高为主,部分患儿异型淋巴细胞增高,早期EBV-VCR-IgM阳性。本组误诊9例,误诊原因主要为早期症状轻、体征少,以其他系统症状为主要表现,或病初即有多脏器受累。结论儿童EBV感染症状和体征多种多样,累及全身各个脏器,容易误诊,EBV-VCR-IgM检测有利于早期诊断。Objective To analyze the clinical manifestations,laboratory examinations and misdiagnosis of Epstein-Barr virus infection in paediatric patients and to improve the diagnosis of EBV infection.Methods Data of 29 children of EBV infection diagnosized by ELISA were retrospective analyzed in our hospital.Results EBV infection was manifested by fever,angine,lymph node enlargement and hepatosplenomealy with possible complications of cough,jaundice,eyelid,skin rashes,convulsion and gastrointestinal bleeding.The laboratory tests showed more increased peripheral blood cell counts,especially in lymphocytes.Alien lymphocytes increased in some patients and early positive EBV-VCR-IgM was detected.9 patients were misdiagnosed because of light early symptoms and limited signs,other system clinical manifestations and multiple organ involvement at early onsets.Conclusion The symptoms and signs of paediatric patients with EBV infection are diverse,involving multiple organs and prone to misdiagnosis.Early detection of EBV-VCR-IgM is conducive to diagnosis.

关 键 词：儿童 爱泼斯坦巴尔病毒感染 实验室技术和方法 

分 类 号：R725.129.204[医药卫生—儿科]