通尿灵治疗前列腺增生症临床疗效观察  

Clinical effects of tadenan on benign prostate hypertrophy

作　　者：吴开俊[1] 黄健[1] 

机构地区：[1]广州医学院第一附属医院

出　　处：《临床泌尿外科杂志》1999年第7期291-292,共2页Journal of Clinical Urology

摘　　要：目的：验证通尿灵治疗前列腺增生症（ＢＰＨ）的临床疗效。方法：选择经临床确诊的ＢＰＨ患者５９例，口服通尿灵５０ｍｇ，２次／ｄ，共８周。分别于用药前、治疗后４周及８周行国际前列腺症状评分（ＩＰＳＳ）、尿流率、残余尿量、血清前列腺特异性抗原（ＰＳＡ）及前列腺体积等指标测定，同时对出现的副作用进行记录。结果：用药８周后ＩＰＳＳ平均降低６．２３分，尿流率平均升高４．８ｍｌ／ｓ，残余尿量平均减少２１．７９ｍｌ，ＰＳＡ均降至正常，前列腺体积无明显变化。５９例中仅１例出现轻微的消化道不适症状。结论：通尿灵对改善ＢＰＨ患者主观症状、客观体征和提高生活质量有明显效果，副作用及不良反应少。Purpose: To verify the clinical effects of tadenan on benign prostate hypertrophy (BPH). Methods: 59 cases of BPH as diagnosed were selected.tadenan was administered orally with the recommended dose of 50 mg,twice daily over 8 weeks.IPSS, urine flow rate,residual urine volume,PSA and prostate volume were measured and the drug side effects were recorded before,4 weeks and 8 weeks after administration respectively. Results: 8 weeks after administration,on an average,IPSS decreased by 6.23,urine flow rate increased by4.8ml/s,residual urine volume reduced by 21.79 ml,PSA decreased to normal,prostate volume changed little.1 among 59 cases appeared mild gastrointestinal disturbance. Conclusions: tadenan can dramatically improve symptoms,signs and life qualities of patients with BPH.The side effects attributed to tadenan are less common.

关 键 词：通尿灵 前列腺增生 药物疗法 疗效 

分 类 号：R697.320.5[医药卫生—泌尿科学]