固相萃取地表水中痕量联苯胺及HPLC-MS测定  

Determination of trace amounts of benzidine in surface water by HPLC-MS/MS with solid phase extraction

作　　者：杨秋红[1] 钱蜀 程小艳[2] 宋倩[1] 吕航[1] 但德忠[1] 

机构地区：[1]四川大学建筑与环境学院,四川成都610065 [2]四川省环境监测中心站,四川成都610041

出　　处：《化学研究与应用》2011年第1期102-106,共5页Chemical Research and Application

摘　　要：采用固相萃取及高效液相色谱-串联质谱技术,建立了地表水中痕量联苯胺的测定方法。水样经HLB固相萃取柱富集,二氯甲烷与丙酮(1∶1,v/v)洗脱,氮吹后转为甲醇溶剂,以液相色谱串联质谱选择离子监测(SRM)模式定性、定量分析。在本实验条件下,加标回收率在72.0%～94.0%之间,相对标准偏差8.1%～9.8%(n=7)。检出限为1.0×10-3μg/L,较文献报道的检出限低。方法已用于环境水样的日常监测。A novel method for determination of trace amounts of bendizine in surface water by HPLC-MS/MS with solid-phase extraction was developed.Sample was concentrated by HLB extraction cartridge,then eluted with dichloromethane and acetone eluants.The solvent was changed into methanol after nitrogen blow.Quality and quantity analysis was carried out by HPLC-MS/MS with SRM mode.Under the experimental condition,the recoveries and relative standard deviations（RSD,n=7） were 72.0%~94.0% and 8.1%~9.8% respectively.The detection limit was 1.0×10-3μg/L,which was lower than others reported in literatures.

关 键 词：联苯胺 高效液相色谱-串联质谱 固相萃取 地表水 

分 类 号：O657.7[理学—分析化学]