经胃镜球囊扩张治疗贲门失弛缓症90例临床效果观察  

Clinical effect of endoscopic pneumatic balloon dilation in the treatment of achalasia of cardia

作　　者：黄锦文 李晓林 梁碧云 付茁 

机构地区：[1]深圳市龙华人民医院内科,广东深圳518000

出　　处：《海南医学》2011年第3期98-100,共3页Hainan Medical Journal

摘　　要：目的探讨经胃镜球囊扩张治疗贲门失弛缓症(AC)的临床效果。方法将90例确诊的AC患者随机分为两组,扩张组(n=45例)经胃镜球囊扩张(Endoscopic balloon pneumatic dilation,EPD)治疗,手术组(n=45例)行外科手术治疗。术后1、3、6、9、12个月各随访1次,此后每年随访1次,对两组的疗效、随访资料进行对比分析。结果两组有效率、并发症发生率,扩张组为93.3%和11.1%,手术组为95.6%和13.3%;扩张组、手术组累积复发率分别为24.4%和17.7%;两组比较差异均无统计学意义(P>0.05)。每例次平均住院日和住院费,扩张组分别为6.1d和4311.5元,手术组为17.8d和11972.1元,两组比较差异均有统计学意义(P<0.05)。结论 EPD治疗AC,因其疗效确切、安全性高、操作简单且住院时间和费用显著低于手术治疗,是治疗AC较为理想的首选和主要方法。Objective To investigate clinical effect of endoscopic pneumatic balloon dilation（EPD）in the treatment of achalasia of cardia（AC）. Methods 90 cases with AC were randomly divided into two groups： expanded group （45 cases） who received the treatment of EPD and EST（45 cases） who received esophageal sphincterotomy （EST）.The patients were followed-up at 1, 3, 6, 9 and 12 months after procedure. and then followed-up one time every year. The treatment outcomes of EPD and EST were compared and analyzed. Results The effective percentage and the rate of complication were 93.3% and 11.1% in group PBD;95.6% and 13.3% in group EST respectively; the rate of accumulation recurrence were 24.4% in group EPD and 17.7% in group EST, and there was no statistical significance between two group. The average days and the costs of hospitalization are 6.1days and 4311.5 yuan in group EPD, 17.8 days and 11972.1 yuan in group EST, and there was a statistical significance（P0.05）. Conclusion EPD is an effective, safe and simple method for the treatment of AC, with less suffering and hospitalization days and cost, and hence is the ideal and main choice to treat AC.

关 键 词：贲门失弛缓症 内镜球囊扩张 手术治疗 

分 类 号：R655.4[医药卫生—外科学]