中风证候要素与神经功能缺失评分的相关性研究  

Correlation between stroke syndrome factors and neurological impairment scores

作　　者：陈宝鑫[1] 张允岭[1] 郭蓉娟[1] 陈志刚[1] 邹忆怀[2] 邹敬韬[3] 曹晓岚[4] 张玉莲[5] 赵建军[6] 陈志强[7] 常富业[8] 

机构地区：[1]北京中医药大学东方医院,北京100078 [2]北京中医药大学东直门医院 [3]吉林大学药学院 [4]山东中医药大学附属医院 [5]天津中医药大学第二附属医院 [6]长春中医药大学第一附属医院 [7]河北医科大学中医院 [8]煤炭总医院

出　　处：《北京中医药大学学报》2011年第1期68-72,共5页Journal of Beijing University of Traditional Chinese Medicine

基　　金：国家重点基础研究发展计划(973计划)项目(No.2006CB504805)

摘　　要：目的研究中风证候要素与神经功能缺失评分的相关性。方法纳入脑梗死急性期患者163例,收集中医四诊信息,根据《中风病辨证诊断标准》提取证候要素。神经功能缺失评分采用美国国立卫生院卒中量表(NIHSS)。结果火、痰、气虚得分与NIHSS评分呈正相关。随着证候要素相兼数的增多,NIHSS评分逐渐增高,两者的相关系数(r)为0.218(P<0.05)。入院时风、痰、血瘀患者最多,经治疗后风证、血瘀证患者病例数明显减少,其余证候改善不明显。具有某一证候要素的患者在入院时与入院14 d,NIHSS评分无明显差异。入院14 d后大部分患者证候要素得分与NIHSS评分呈不同程度的下降,各证候要素得分与NIHSS评分变化情况无统计学差异。结论证候要素的得分、相兼与神经功能缺损具有一定的相关性。中风证候要素的得分及组合的复杂性、多样性能在一定程度上反映中风病情的严重程度。Objective To study the correlation between stroke syndrome factors of stroke and neurological impairment scores.Methods The patients with acute cerebral infarction（n=163） were chosen and the information of TCM four diagnostic methods was collected.The syndrome factors were extracted according to the Stroke Syndrome Diagnostic Criteria,and neurological impairment was scored according to the National Institutes of Health Stroke Scale（NIHSS）.Results The scores of fire,phlegm and qi-deficiency were correlated to the scores of NIHSS.The scores of NIHSS increased gradually as the number of concurrent syndrome factors increasing and the correlation coefficient（r） between them was 0.218（P0.05）.Most patients were those with wind,phlegm and blood stasis when they just hospitalized,and after the treatment the numbers of patients with wind or blood stasis decreased significantly but those with other syndrome factors had no changes.The scores of NIHSS had no significant difference in the patients with one of syndrome factors when they just hospitalized and hospitalized for 14 days.After hospitalized for 14 days the most of the patients had less scores of syndrome factors and NIHSS but the changes of syndrome factor scores and NIHSS scores had no statistical difference.Conclusion The scores and concurrent of syndrome factors are correlated to neurological impairment.The complexity and diversity of scores and combination of stroke syndrome factors can reflect the severity of stroke to a certain extent.

关 键 词：中风 证候要素 神经功能缺失评分 相关性 

分 类 号：R255.2[医药卫生—中医内科学]