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作 者:骆晓艳[1,2] 曲江文[2] 丁亚兴[2] 田宏[2] 雷玥[2] 高志刚[2] 齐秀英[1]
机构地区:[1]天津医科大学,天津300011 [2]天津市疾病预防控制中心
出 处:《现代预防医学》2011年第4期739-741,共3页Modern Preventive Medicine
摘 要:[目的]分析天津市婴儿麻疹流行状况及相关因素,为控制麻疹提出策略。[方法]对天津市历年法定传染病报告系统麻疹监测数据和流行病学调查资料进行分析,用酶联免疫吸附试验(ELISA)间接法检测麻疹IgG抗体。[结果]天津市麻疹发病显示明显的年龄分布特点,2005~2009年间均是1岁以下婴儿发病率最高,婴儿麻疹占麻疹病例的构成比呈增高趋势。73.97%的8月龄~1岁婴儿麻疹病例未进行过免疫接种。8月龄以下婴儿随月龄增长抗体阳性率逐渐下降,7月龄时抗体阳性率降至16.67%。医院就诊史与1岁以下婴儿麻疹有关,OR=15.4。[结论]天津市2005~2009年间麻疹发病均是1岁以下婴儿发病率最高,婴儿麻疹占麻疹病例的构成比呈增高趋势。未及时免疫、麻疹胎传抗体的滴度低以及医院就诊史等因素可能与婴儿麻疹发病有关。[Objective] To understand epidemic status and the associated factors of measles in infants in Tianjin,so as to provide strategies for the control of measles.[Methods] Measles surveillance data and survey data were analyzed by using epidemiological method.IgG antibody against measles were detected in infants by ELLSA.[Results] The incidence of measles in infants aged below one year was the highest in annual year,and the constituent ratios of infant measles cases to all cases increased from 2005 to 2009.73.97% of measles cases aged from eight month to one year were not immunized by measles vaccine.IgG antibody against measles from mother in infants aged below eight months old decreased along with the growing of month.The positive rate of IgG antibody in infants aged seven months old decreased to 16.67%.History of visiting hospital was significantly related to measles,and its OR was 15.4.[Conclusion] The incidence of measles in infants aged below one year is the highest and the constituent ratios of infant measles cases to all cases increased from 2005 to 2009.Lack of immunization,lower level of antibody against measles from mother and the history of visiting hospital were associated with the high risk of the infant measles.
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