受损背根节神经元自发放电节律的整数倍模式及其动力学变化  

PATTERN AND DYNAMIC CHANGES OF INTEGER MULTIPLES IN SPONTANEOUS DISCHARGE OF INJURED DORSAL ROOT GANGLION NEURONS

作　　者：龙开平[1] yahoo.com 胡三觉[2] 段玉斌[3] 徐晖[3] 

机构地区：[1]第四军医大学物理教研室 [2]第四军医大学神经科学研究所,西安710032 [3]第四军医大学生理教研室,西安710032

出　　处：《生理学报》1999年第5期481-487,共7页Acta Physiologica Sinica

基　　金：国家自然科学基金!39740029

摘　　要：本文记录了大鼠损伤背根节神经元的自发放电活动。采用背根节慢性压迫动物模型，记录慢性压迫手术后3～10d背报节的自发放电。在记录的156根纤维中，观察到17根（占11％）出现的动作电位峰峰间期（ISI）以某一基础间期的整数倍模式出现的整数倍时间节律形式，其回归映射图为晶格状点阵结构，并且该时间形式受细胞膜上钠、钾通道的调控。上述结果表明：某些直观看似不规则的放电时间序列是有着内在的结构和规律性的，这种规律取决于膜上通道和内环境的状态。For the purpose of the Present investigation, spontaneous discharges of dorsal rootganglion (DRG) neurons of the rats, which had undergone 3~10 days' chroniccompression, were studied. It was found that the interspike interval (ISI) of 17 out of156 fibers had integer multiples temporal rhythm pattern, in which all the ISI were integermultiples of a basic ISI and a return map of their ISI could be constructed as a crystal gridstructure. This temporal pattern could be modified by Na+ channel and K+ channel ontheir membranes. These data indicated the presence of some irregular discharge trainswith their intrinsic regularity.

关 键 词：自发放电 动作电位间期 神经信息编码 整数倍 

分 类 号：Q424[生物学—神经生物学]