6年间溶血葡萄球菌的变迁与耐药性分析  

Analysis of Staphylococcus haemolyticus's evolution and drug resistance in 6 years

作　　者：张青锋[1] 张姝潇 

机构地区：[1]浙江省遂昌县人民医院检验科,遂昌323300

出　　处：《中国抗生素杂志》2010年第12期934-936,共3页Chinese Journal of Antibiotics

摘　　要：目的调查医院临床分离的溶血葡萄球菌分布特点及耐药状况,为溶血葡萄球菌医院感染的预防与控制提供可靠依据。方法对我院2004—2009年临床分离各类标本的葡萄球菌分布进行统计,并对溶血葡萄球菌进行药敏分析。结果 6年中溶血葡萄球菌呈直线上升;甲氧西林耐药溶血性葡萄球菌(MRSH)比率高,对大部分临床常用抗菌药物耐药非常严重;对利福平、四环素耐药率较低,未发现耐万古霉素溶血葡萄球菌。结论溶血葡萄球菌耐药情况严重,分离量已居葡萄球菌分离株之首,临床医生应对此给予足够的重视。Objective To investigate the distribution and antibiotic resistance of clinical isolates of Staphylococcus haemolyticus for prevention and control of nosocomial infections by S.haemolyticus.Methods The distribution of Staphylococcus were analyzed and the susceptibility test was carried out in the hospital investigated during 2004~2009.Results The detection rate of S.haemolyticus linearly increased;the ratio of methicillin-resistant S.haemolyticus（MRSH） was high;multi-resistance of S.haemolyticus was serious against commonly used antimicrobials except rifampicin and tetracycline,and no vancomycin-resistant S.haemolyticus was detected.Conclusion The isolated rate of S.haemolyticus was the highest in staphylococci and its antibiotic resistance was serious,which should be concerned in clinic.

关 键 词：溶血葡萄球菌 耐甲氧西林溶血葡萄球菌 耐药性 医院感染 

分 类 号：R378.11[医药卫生—病原生物学]