青海省2000～2009年急性驰缓性麻痹病例与健康人群病原学监测  

ETIOLOGICAL SURVEILLANCE ON ACUTE FLACCID PARALYSIS (AFP) CASES AND HEALTHY CROWDS FROM 2000 TO 2009 IN QINGHAI PROVINCE

作　　者：赵生仓 

机构地区：[1]青海省疾病预防控制中心,西宁810007

出　　处：《现代预防医学》2011年第3期552-553,共2页Modern Preventive Medicine

摘　　要：[目的]分析开展急性驰缓性麻痹(AFP)病例、健康人群粪便标本病原学监测结果,为保持无脊灰状态提供实验室依据。[方法]病毒分离及鉴定,脊灰病毒株型内鉴别,确定疫苗株或野病毒株。[结果]青海省2000～2009年AFP病例、健康人群粪便标本1613份,分离出脊髓灰质炎病毒22株,分离率为1.36%,其中脊灰I型疫苗株3株,脊灰II型疫苗株2株,脊灰III型疫苗株9株,脊灰混合型疫苗株8株,无脊灰野病毒株。分离到非脊灰肠道病毒(NPEV)187株,分离率为11.59%。[结论]该省2000～2009年无本地脊灰野毒株病例流行,阻断了脊灰本地野病毒的传播,保持了无脊灰状态。[Objective] To provide the laboratory basis for maintaining polio-free status through the etiological surveillance of stool specimens of acute flaccid paralysis （AFP） cases and healthy crowds. [Methods] Virus isolation and identification were used, and the strains were determined by intratypic differentiation of poliovirus. [Results] 1 613 stool specimens of AFP cases and healthy crowds were detected from 2000 to 2009 in Qinghai Province, and 22 strains of poliovirus were isolated, the isolation rate was 1.36% , including 3 strains of poliovirus type I vaccine strain, 2 strains of poliovirus type II vaccine strain, 9 strains of poliovirus type III vaccine strain, 8 strains of hybrid poliovirus vaccine strain, and no wild poliovirus strain. Furthermore, 187 strains of non-polio enteroviruses （NPEV） were isolated, and the isolation rate was 11.59%. [Conclusion] There is no prevalence of local wild poliovirus from 2000 to 2009 in Qinghai Province, which illustrates that we block the spread of local wild poliovirus effectively, and maintain polio-free status.

关 键 词：脊髓灰质炎病毒 非脊灰肠道病毒 病原学监测 

分 类 号：R512.4[医药卫生—内科学]