用EP-7A文件评价维生素C对两种微量血糖仪的干扰  

Interference of Vitamin C on Two Kinds of Trace Glucose Meter with EP-7 A Guideline

作　　者：石文[1] 陈富[1] 邱峰[1] 周强[1] 

机构地区：[1]广东省中医院二沙分院检验科,广州510105

出　　处：《现代检验医学杂志》2010年第6期156-157,共2页Journal of Modern Laboratory Medicine

摘　　要：目的 用EP-7A指南探讨维生素C（VitC）对美国雅培安妥超越微量血糖仪和德国拜尔拜安易微量血糖仪测定血糖的影响.方法 采用倍比稀释方法得到含有不同浓度VitC的血清,以正常混合血清为对照组,用两台微量血糖仪及罗氏Cobsa400生化分析仪同时进行血糖测定,对其结果进行比较、分析.结果 维生素C的浓度对两微量血糖仪测量结果的回归方程分别为Y= 0.282 7X＋4.417,Y=0.198X＋4.21.结论 维生素C对两种微量血糖仪都产生正干扰,而对罗氏Cobas400生化分析仪无干扰.因此在测定结果与临床症状不符的情况下,应尽可能采用不同的方法测定,或停用干扰性药物一段时间后再测定血糖.Objective To investigate the interference of Vitamin C（VitC） on two kinds of trace glucose meter according to EP-7A. Methods Two-fold dilution was applied to obtain series serum contain different concentrations of VitC,and the mixed normal serum was as the control. Glucose concentration of samples was teste with two trace glucose meters and Roche Cobas 400 plus and the results were analyzed. Results To EP-TA,the relationship between A and B of VitC express,Y=0. 282 7X＋4. 417 and Y=0. 198X＋4. 21. Conclusion VitC had interference on the two trace glucose meter, and no interference on cobsa400 inplus. The interference on the detection of blood glucose could not be ignored. So when the result and clinical sysmptoms are not match,different ways should be used to conform the results.

关 键 词：维生素C 微量血糖仪 干扰 

分 类 号：R446[医药卫生—诊断学]