脑SPECT显像和CT扫描观察高压氧治疗脑外伤后综合征疗效  

Comparative study of cerebral blood perfusion SPECT imaging and CT scan in evaluation of the curative effect of hyperbaric oxygen in patients with post traumatic brain syndrome

作　　者：汤中泉[1] 孙达[2] 张蕴秋[1] 刘文明[1] 王美玲[1] 

机构地区：[1]浙江大学医学院第二附属医院高压氧科,310009 [2]浙江大学医学院第二附属医院核医学科

出　　处：《中华核医学杂志》1999年第4期213-215,共3页Chinese Journal of Nuclear Medicine

摘　　要：目的　对比研究脑外伤后综合征患者在高压氧（ＨＢＯ） 治疗前后的脑ＳＰＥＣＴ和脑ＣＴ扫描结果，并对两者的临床意义及其优越性进行评价。方法　２８８ 例脑外伤后综合征患者接受２ ～４ 个疗程的ＨＢＯ治疗，并在治疗前后用９９Ｔｃｍ双半胱乙酯（ＥＣＤ）ＳＰＥＣＴ和ＣＴ进行疗效监测和对比分析。结果　治疗前脑ＳＰＥＣＴ阳性率为８０－６ ％ ，而ＣＴ阳性率仅为１０－２％ 。治疗后ＳＰＥＣＴ示９０％ 异常得到改善，表明ＨＢＯ 治疗可明显改善局部脑血流（ｒＣＢＦ） 。显示ＳＰＥＣＴ在监测ＨＢＯ 疗效方面有一定的优越性。Objective To comparatively study the results of cerebral SPECT and cerebral CT before and after hyperbaric oxygen (HBO) treatment in post traumatic brain syndrome Methods HBO was used to treat 288 patients with post traumatic brain syndrome for two courses, and made therapeutic surveillance and comparative analysis with 99 Tc m ECD SPECT, CT before and after treatment Results Before treatment, the positive rate of cerebral SPECT was 80 6%, but the positive rate of CT was only 10 2%; after treatment, 90% of SPECT became negative, and the clinical symptoms of the patients disappeared as SPECT became negative The results showed that HBO treatment could evidently improve rCBF, and showed that SPECT was superior to CT in surveillance of HBO treatment Conclusions 99 Tc m ECD SPECT could play an important role in the diagnosis of post traumatic brain syndrome and the therapeutic surveillance of HBO

关 键 词：脑损伤 SPECT CT 高压氧治疗 

分 类 号：R651.150.5[医药卫生—外科学] R459.6[医药卫生—临床医学]