核素胃排空在近端胃手术中的实验研究  

Radioisotope gastric emptying after proximal gastrectomy:experimental studies

作　　者：何勇[1] 张永学[1] 高再荣[1] 陈先祥[2] 

机构地区：[1]同济医科大学附属协和医院核医学科,武汉430022 [2]同济医科大学附属协和医院,武汉430022

出　　处：《放射学实践》1999年第4期264-266,共3页Radiologic Practice

摘　　要：目的 :探讨近端胃手术不同术式后胃排空功能的改变 ,应用SPECT液体胃排空方法测定胃半排时间(GEt1/ 2 )。方法 :40只大白鼠分成 4组 ,每组均行选择性迷走神经干切断术 ,A组未另附加其它术式 ,B组附加幽门成形 ,C组行近端胃切除 ,D组行近端胃切除附加幽门成形 ,术前及术后 1、2、3周分别行核素胃排空显像测定GEt1/ 2 。结果 :各组内手术前后比较 ,术后第 1周各组GEt1/ 2 均明显延迟 ,术后第 2周C组及D组恢复 ,术后第 3周B组恢复但A组仍明显延迟 ;A组与B组、B组与D组比较 ,术后各时间点均有极显著性差异 ;C组与D组比较 ,除第 2周外 ( 0 0 1<P <0 0 5 )其余各时间点无显著性差异。结论 :核素胃排空显像能准确地反映迷走神经切断术 ,近端胃切除术及幽门成形术对胃排空功能的影响 。Objective:The Gastric half emptying Time(GEt 1/2 )was determined with SPECT gastric emptying of liquids imagine.Our aim was to study how gastric emptying function changes after different modes of proximal gastrectomy.Methods:Forty SD female rats undergone selective truncal vagotomy were randomized into four groups:A without additional operation;B with pyloroplasty;C with proximal gastrectomy;D with both proximal gastrectomy and pyloroplasty.GEt 1/2 was quantitatively assessed with SPECT technique in preoperation and 1,2,3 weeks postoperatively.Results:Compared with different periods before and after operation,GEt 1/2 of each group significantly delayed in first week after operation,in 2nd weeks postoperatively, group C and D recovered, on 3rd week group B began to recover but group A remained to be significantly delayed.There were highly significant differences between group A and B,group B and D in the three point surgey( P <0 01),there were no significant difference between group C and group D,except significant difference in the second week.Conclusions:Gastric emptying imaging can be used to determine emptying function after truncal vagotomy,proximal gastrectomy and pyloroplasty.It has evident significance to evaluate postoperative gastric motility function and determine what kind of operation should be carried out.

关 键 词：胃排空 核素显像 近端胃切除 

分 类 号：R816.5[医药卫生—放射医学] R656.61[医药卫生—临床医学]