2007年-2009年上海市闵行区流感监测结果分析  

Analysis of influenza surveillance in Minhang district during 2007-2009

作　　者：杨丽华[1] 王小光[1] 高烨[2] 赵百惠[2] 沈佳仁[2] 

机构地区：[1]上海市闵行区疾病预防控制中心,上海201101 [2]上海市疾病预防控制中心,上海200336

出　　处：《中国卫生检验杂志》2010年第12期3141-3144,共4页Chinese Journal of Health Laboratory Technology

摘　　要：目的:了解上海市闵行区2007年-2009年度人群流感的流行特征,为本地区流感预防控制工作提供科学依据。方法:收集、汇总闵行区流感监测哨点的流感样病例数、就诊人数等数据进行描述性流行病学分析;对采集的流感样病例咽拭子标本用狗肾传代细胞进行流感病毒分离、培养,用红细胞凝集抑制实验鉴定流感病毒型和亚型。结果:2007年-2009年监测到流感样病例总数为7938例,流感样病例平均就诊比例为0.52%。,采集标本1277份,分离到各型流感毒株406株。2007年优势株为季节性H3N2,2008年优势株为季节性H1N1与B型(Yamagate系)共同流行,病毒分离及流行病学监测都显示2007年-2008年闵行区流感流行大致呈冬春季和夏季高发的特点。2009年冬春、夏季流感发病高峰不明显,但在11月-12月出现全年流感流行高峰,病毒分离结果显示冬春季为季节性H3N2、H1N1共同流行,夏秋季开始以季节性H3N2、甲型H1N1在人群中同时流行,之后以甲型H1N1为主。结论:2007、2008年闵行地区流感流行特点为冬春季和夏季高发,病毒优势株呈季节性H3N2、B、H1N1交替流行态势。2009年秋冬季暴发甲型H1N1流感疫情,9月-12月甲型H1N1毒株占全年检出毒株数的50%.Objective：To understand the influenz epidemic characteristics of population in Minhang from 2007 to 2009,to provide scientific bases for the prevention of influenz.Methods： Collecting surveillance data of influenza-like illness（ILI） in monitored hospital of Minhang.All taking specimens were processed to culture and isolate the influenz virus in MDCK cell,and identified type and subtypes using the haemagglutination inhibition test（HI）.Results： Totally 7938 cases ILI were reported in monitored hospital from 2007 to 2009,the doctor ratio of cases ILI were 0.52%.Taking specimens were 1277,406 strains of influenz virus were isolated.The dominant epidemic strain of influenz virus was seasonal H3N2 in 2007,seasonal H1N1 and B co-circulated in 2008.Both of influenz surveillance and identification of influenz virus showed that the high incidence of influenz was in winter-spring and summer from 2007-2008.The two seasonal influenza peaks of winter-spring and summer were obvious in 2009,but the epidemic peak of influenz was apparent in November and December,The seasonal influenza H1N1 and H3N2 co-circulated in the winter-spring.In summer-autumn,influenza A（H1N1） and the seasonal H3N2 co-circulated in Minhang,then influenza A（H1N1） became dominating.Conclusion： The epidemic peaks of influenza were winter-spring and summer-autumn in Minhang Area from 2007 to 2008,the dominant strains was alternation between H3N2,B and H1N1.The outbreak caused by influenza A（H1N1） was reported in autumn-winter in 2009,the detection ratioe of Influenza A（H1N1） virus was 50%.

关 键 词：流行性感冒(流感) 流感病毒 监测 甲型H1N1 

分 类 号：R373.13[医药卫生—病原生物学]