72株院内感染鲍曼不动杆菌ESBL检测及耐药性分析  

Detection of extended-spectrum β-lactamases and drug resistance in 72 strains of Acinetobacter baumannii

作　　者：马全玲[1] 武大伟[1] 魏殿军[1] 

机构地区：[1]天津医科大学第二医院检验科,天津300211

出　　处：《中国卫生检验杂志》2010年第12期3404-3405,共2页Chinese Journal of Health Laboratory Technology

基　　金：天津市卫生局科技基金资助项目(06KZ31)

摘　　要：目的:了解天津地区鲍曼不动杆菌(以下简称Ab)耐药的趋势。方法:分析2007年5月-2008年3月分离自天津地区医院患者标本的鲍曼不动杆菌耐药性及其产超广谱Β-内酰氨酶(ESBL)情况。结果:共分离到鲍曼不动杆菌72株,以呼吸道感染为主,ESBL阳性株16(22.2%)对亚胺培南耐药率最低(11%)。结论:鲍曼不动杆菌产ESBL,亚胺培南治疗鲍曼不动杆菌感染效果好,警惕并重视鲍曼不动杆菌感染,注意病原菌及耐药率的监测,规范抗生素应用,保持敏感抗生素的抗菌活性。Objective：To analyze the antibiotic resistence tendency of Acinetobacter baumannii（Abi）in Tianjin.Methods： The results of antimicrobial susceptibility test（AST） and ESBL of 72 identified Abi strains from May,2007 to March,2008 were summarized retrospectively.Results： All together separates Acinetobacter baumannii bacillus 72,which was collected from the respiratory infections primarily.The most sensitive drugs tested for Abi in vitro were Imipenem（IPM）.Conclusion： Imipenem is the most effective antibiotics for the treatment of Acinetobacter baumannii infections.Pay attention to the importance of Acinetobacter baumannii infections,and monitoring of the pathogens and the rate of resisitance,standard the antibiotics applications,maintain sensitive antibiotics′s activity of antibiotics.

关 键 词：鲍曼不动杆菌 抗生素 耐药性 

分 类 号：R378[医药卫生—病原生物学]