河南省啮齿类动物肾综合征出血热免疫学调查研究  

Study on the characteristics of the rodents hosts for hemorrhagic fever with renal syndrome in Henan province

作　　者：张爱梅[1] 孙建伟[1] 王海峰[1] 梁明辉[2] 卫海燕[1] 李林红[1] 张彦平[3] 李新民[1] 张永振[3] 郝宗宇[1] 

机构地区：[1]河南省疾病预防控制中心,郑州450016 [2]洛阳市疾病预防控制中心,河南洛阳471000 [3]中国疾病预防控制中心,北京102206

出　　处：《中国卫生检验杂志》2010年第12期3443-3445,共3页Chinese Journal of Health Laboratory Technology

基　　金：国家"十五"重大科技攻关科研基金(2003BA712A08-02)

摘　　要：目的:研究河南省啮齿类动物携带肾综合征出血热病毒状况,为肾综合征出血热防治研究提供科学依据。方法:笼捕法捕鼠,用直接免疫荧光法检测肺组织切片。结果:在河南省不同生境的7个县(区、市)共布鼠笼6429个,捕获啮齿类动物697只,褐家鼠为优势鼠种,占33.53%。其次为黄胸鼠,占18.41%。应用直接免疫荧光法检测全部鼠肺,其中肾综合征出血热病毒阳性肺组织切片97份,阳性率为13.92%。阳性切片中,褐家鼠和仓鼠分别占47.0%和26.32%。结论:河南省不同地区肾综合征出血热病毒的主要宿主动物是褐家鼠。Objective：To study the characteristics of the rodents hosts for hemorrhagic fever with renal syndrome in Henan province.Methods： Detection the infection of the hosts for hemorrhagic fever with renal syndrome with direct immunofluorescence assay.Results： 6429 cages were put in seven different habitats in Henan province and 697 rodents hosts were captured.The majority were Rattus norvegicus（33.53%）,and the next were Rattus flavipectus（18.41%）.97 samples were positive in the direct immunofluorescence assay（DFA） of all the rodents hosts lungs,and the positive rate was 13.92%.The proportion of Rattus norvegicus and Hamster were 47.0% and 26.32% in the 97 positive samples.Conclusion： Rattus norvegicus was the main rodents hosts for hemorrhagic fever with renal syndrome in Henan province.

关 键 词：肾综合征出血热 汉坦病毒 直接免疫荧光 

分 类 号：R512.8[医药卫生—内科学]