炎热清胶囊质量标准研究  

Study on Quality Standard of Yanreqing Capsule

作　　者：满喜霞 丁红强 林恒宽 袁锐利 

机构地区：[1]河南辅仁医药科技开发有限公司,河南郑州450003

出　　处：《中国药业》2010年第22期41-43,共3页China Pharmaceuticals

摘　　要：目的建立炎热清胶囊的质量标准。方法用薄层色谱(TLC)法鉴别黄芩和栀子;用高效液相色谱(HPLC)法测定黄芩的主要成分黄芩苷的含量。结果薄层色谱斑点清晰,阴性无干扰;黄芩苷对照品质量浓度在0.057～0.133 g/L范围内与峰面积线性关系良好(r=0.999 86),平均加样回收率为99.79%,RSD为1.03%(n=6)。结论定性定量方法简便、准确、重复性好,可用于炎热清胶囊的质量控制。Objective To establish the quality standard for Yanreqing Capsule.Methods Radix Scutellariae and Fructus Gardeniae in the pre-scription were qualitatively identified by TLC.The content of effective substance baicalin in the preparation was determined by HPLC.Results The developed TLC spots were fairly clear,and the blank test showed no interference.The linear range of baicalin was 0.057-0.133 mg/mL（r = 0.999 86）,and the average recovery rate was 99.8% with RSD = 1.0%（n = 6）.Conclusion This qualitative and quantitative method is simple,accurate and reproducible,which can be used for the quality control of Yanreqing Capsule.

关 键 词：黄芩苷 高效液相色谱法 炎热清胶囊 薄层色谱法 质量标准 

分 类 号：R284.1[医药卫生—中药学] R286.0[医药卫生—中医学]