具有生物活性的磷杂环化合物研究——ⅩⅣ.Lawesson试剂与含活泼氢的双官能团化合物的环化反应  

Study on Biologically Active Phosphorus Heterocycles——XIV. Cyclization Reactions of Lawesson' s Reagent with Bifunctional Compounds Containing Mobile Hydrogens

作　　者：何良年[1] 李凯[1] 卓仁禧[2] 刘小鹏[1] 吴田捷[1] 陆爱红[1] 

机构地区：[1]华中师范大学有机合成研究所,武汉430079 [2]武汉大学化学系,武汉430072

出　　处：《化学学报》1999年第9期1026-1033,共8页Acta Chimica Sinica

基　　金：武汉市青年科技晨光计划;湖北省自然科学基金资助项目

摘　　要：研究Lawesson试剂与含活泼氢的双官能团化合物的环化反应,合成了O-P-O,N-P-O,N-P-N型五元、六元及七元磷杂环.探讨了其成环可能性及其环化机理.初步的生物活性测定结果表明,应用Lawesson试剂所合成的磷杂环具有较好的选择性除草活性.Five, six, and seven-membered phosphorus heterocycles containing "O-P-O" or "N-P-N" or "N-P-O" bonds were synthesized using cyclization reactions of Lawesson' s reagent with bifunctional compounds containing mobile hydrogens. A cyclization mechanism was also proposed. The results of preliminary bioassays show that phosphorus heterocycles prepared have good selective herbicidal activity.

关 键 词：LAWESSON试剂 环化反应 磷杂环 除草活性 除草剂 

分 类 号：O627.51[理学—有机化学] TQ457.29[理学—化学]