金属锡和三甲基氯硅烷存在下芳香醛、酮与醇的还原-偶联-醚化反应  

The Reduction-Coupling-Etherification of Alcohols and Aromatic Aldehydes or Ketones in the Presence of Tin and Chlorotrimethylsilane

作　　者：吴世晖[1] 王存[1] 高翔[1] 陈元梅 丁宗彪[1] 

机构地区：[1]复旦大学化学系,上海200433

出　　处：《化学学报》1999年第10期1152-1161,共10页Acta Chimica Sinica

摘　　要：在三甲基氯硅烷(TMSCl)、四氢呋喃(THF)体系中,芳香醛、酮和醇在金属锡的作用下发生还原-偶联-醚化反应生成相应的频那醇二醚类化合物.文中对此反应的应用范围进行了探讨,并提出了合理的反应机理.A reduction-coupling-etherification reaction between aromatic aldehydes or ketones (1) and alcohols ( 2 ) to yield corresponding diether ( 3 ) of pinacol in the presence of tin and chlorotrimethylsilane. The scope and limitations of this reaction were studied and a reasonable mechanism was proposed.

关 键 词：锡 三甲基氯硅烷 偶联 醚化 频那醇二醚 

分 类 号：O623.423[理学—有机化学]