雪松胺醇-硼烷络合物催化的潜手性酮的不对称还原反应  

Asymmetric Reduction of Prochiral Ketones Catalyzed By Borane Amino Hydroxycedrane Complex

作　　者：阎伟[1] 宋一麟[1] 陶凤岗[1] 

机构地区：[1]复旦大学化学系,上海200433

出　　处：《应用化学》1999年第4期74-76,共3页Chinese Journal of Applied Chemistry

基　　金：国家自然科学基金

摘　　要：A novel chiral amino alcohol ligand, (1 R,2R,5S,7R,8R,9S ) 9 amino 8 hydroxycedrane was synthesized from cedranediol and reacted with borane to form the corresponding complex, oxazaborolidine, that was used as catalyst in the asymmetric reduction of prochiral ketones. Medium stereoselectivities were obtained.A novel chiral amino alcohol ligand, (1 R,2R,5S,7R,8R,9S ) 9 amino 8 hydroxycedrane was synthesized from cedranediol and reacted with borane to form the corresponding complex, oxazaborolidine, that was used as catalyst in the asymmetric reduction of prochiral ketones. Medium stereoselectivities were obtained.

关 键 词：潜手性酮 不对称还原 雪松胺醇 硼烷 催化剂 

分 类 号：O621.34[理学—有机化学]