直链淀粉-三(3,5-二甲基苯基氨基甲酸酯)手性固定相分离硒代甘油醚对映体  

Optical Resolution of Glycerin Selenides with Amylose-tris-(3,5-dimethylphenylcarbamate) Chiral Stationary Phase

作　　者：于兆文[1] 刘月启[2] 刘快之[1] 蒋生祥[2] 陈立仁[2] 

机构地区：[1]河南大学化学化工学院,开封475001 [2]中国科学院兰州化学物理研究所,兰州730000

出　　处：《分析化学》1999年第10期1164-1167,共4页Chinese Journal of Analytical Chemistry

基　　金：中国科学院重点基金资助课题

摘　　要：合成出了直链淀粉-三(3,5-二甲基苯基氨基甲酸酯)手性固定相.用该固定相首次拆分了一系列硒代甘油醚对映异构体.讨论了流动相组成和样品结构对保留和拆分的影响.A chiral stationary phase was prepared by coating amylose-tas(3,5-dimethylphenylcarbamate) onto aminopropylated silica gel. It was used for the optical resolution of a series of glycerin monoselenides and glycerin bisulfide. All the enantiomers of the monoselenides examined could be resolved but that of the bisulfides couldn' t. The structural character of the samples dial influence chiral resolution as discussed. An interaction model between the stationary phase and the samples was presented.

关 键 词：手性固定相 对映体 HPLC 硒代甘油醚 拆分 

分 类 号：O657.720.3[理学—分析化学] O627.61[理学—化学]