螺旋藻对大鼠体内^(131)I的促排作用研究  

RESEARCHES OF SPIRULINA PLATENSIS ON THE ENHANCED ^(131)I EXCRETION IN RATS

作　　者：王友顺[1] 吴侃[1] 李华青 谢宗华[1] 黎露刚[1] 

机构地区：[1]海军医学高等专科学校预防医学教研室,南京210099

出　　处：《解放军预防医学杂志》1999年第6期419-422,共4页Journal of Preventive Medicine of Chinese People's Liberation Army

基　　金：海军后勤部基金!课题( 课题号:96 -3312)

摘　　要：目的：为了解螺旋藻对放射性碘的促排作用效果，观察了螺旋藻对大鼠甲状腺滞留１３１Ｉ的促排作用。方法：采用β、γ计数测量装置分别对给予１３１Ｉ后不同时间的大鼠甲状腺进行活体及离体测定。结果：当给大鼠１３１Ｉ２４ ｈ 后，供给含１０％ 的螺旋藻饲料，在第９ 天、第１６ 天对活体大鼠甲状腺β计数测定值与给１３１Ｉ普通饲料组比较具有非常显著性差异（ Ｐ＜ ０ ．０１） ；在给予１３１Ｉ后第４７ 天活杀大鼠进行离体甲状腺γ计数，将螺旋藻饲料组与普通饲料组比较仍具有非常显著性差异（ Ｐ＜０ ．０１） 。结论：采用β、γ两种测量装置检测结果表明，螺旋藻对大鼠甲状腺内沉积的１３１Ｉ具有良好的促排作用。Objective:To study the facilitating effect of Spirulina Platensis(SP) on excretion of radioactive iodine, we observed the 131 I excretion to the thyroid on the SP administered rats.Methods:The in vitro and in vivo of rat thyroid radioactivty after the challenge of 131 I were measured by β、γ scintillator.Results:24h after the administration of 131 I, rats of the experimental group were bred on a diet with 10% SP (W/W), with the control group on a normal diet. Significant differences of β-radioactivity between the groups were yielded on the 9th and the 16th day(P<0.01).On the 47th day the rats were sacrificed and thyroids were gathered for γ-radioactivity counting, which also revealed significant difference between the groups(P<0.01). Conclusion:The results showed that SP can drastically foster the discharge of 131 I from the thyroid deposition of rats.

关 键 词：螺旋藻 甲状腺 碘131 放射性物质 促排剂 抗辐射 

分 类 号：R818.052[医药卫生—放射医学] R979.4[医药卫生—临床医学]