唑来膦酸注射液致不良反应1例  

One case of adverse reaction caused by zoledronic acid injection

作　　者：时慧[1,2] 纪立伟[2] 

机构地区：[1]佳木斯大学附属第一医院药剂科,黑龙江佳木斯154002 [2]卫生部北京医院药学部,北京100730

出　　处：《中国药物应用与监测》2010年第6期382-383,共2页Chinese Journal of Drug Application and Monitoring

摘　　要：1例74a女性患者,因严重骨质疏松首次给予唑来膦酸注射液5mg静脉滴注。用药第2天,患者出现头晕、头痛、胸痛、全身关节疼痛加重,BP160/80mmHg,T38.4℃。给予硝酸甘油、吸氧、吲哚美辛、塞来昔布、眩晕宁等对症治疗,14d后患者症状好转。A 74-year-old woman with severe osteoporosis received an intravenous infusion of zoledronic acid injection 5 mg.On day 2,the patient developed dizziness,headache,chest pain and aggravation of arthralgia.Her temperature was 38.4 ℃,and the blood pressure was 160/80 mmHg.The therapy of oxygen inhalation,nitroglycerin,indomethacin,celecoxib and Xuanyunning was given for symptomatic treatment.Fourteen days later,her symptoms improved.

关 键 词：唑来膦酸注射液 药品不良反应 

分 类 号：R595.3[医药卫生—内科学]