原发性甲状旁腺功能亢进症73例诊治分析  

Diagnosis and treatment of primary hyperparathyroidism （ 73 cases）

作　　者：于愿[1] 隋建[1] 陈堃[1] 郑建伟[1] 张俊[1] 申铭[1] 薛新波[1] 

机构地区：[1]华中科技大学同济医学院附属同济医院普外科,武汉430030

出　　处：《临床外科杂志》2010年第7期443-445,共3页Journal of Clinical Surgery

摘　　要：目的 探讨原发性甲状旁腺功能亢进症（PHPT）的诊断及治疗方法.方法 回顾分析我院2000年至2009年间收治的73例PHPT 患者的临床资料.结果 全组血钙均升高,均值（3.05±0.49）mmol/L,最高血钙值均值（3.28±0.62）mmol/L.69例测定甲状旁腺激素（PTH）,全部增高（119.46～5000.00pg/ml）.联合B超、99mTc-MIBI、CT、MIR定位准确率达91.78%.73例均行手术治疗,病理证实甲状旁腺腺瘤72例,甲状旁腺增生1例,部分患者合并甲状腺疾病.术后患者症状改善,血清钙、PTH恢复正常或明显下降.结论 应提高对PHPT的认识,确诊者应尽早手术.Objective To investigate the diagnosis and treatment of primary hyperparathyroidism（PHPT）. Methods The clinical data of 73 PHPT patients treated in our hospital from 2000 to 2009 was analyzed retrospectively. Hypercalcemia was found in all the patients with blood calcium level being（3.05±0.49 ）mmol/L on average and （3.28 ＋ 0.62）mmoL/L at maximum. Parathyroid hormone （PTH） was detected in 69 patients and the result showed the elevated FTH level in all the patients, ranging from 119.46 to 5000 pg/mL. Preoperatively, the 73 patients underwent sonography, 99mTc - MIBI, CT and/or MRI. The overall preoperative image - directed localization rate was 91.78%. Results Parathyroid adenoma was confirmed in 72 patients and parathyroid hyperplasia in 1 patient by pathological exami- nations. After the operation, serum levels of calcium and PTH returned to the normal and the symptoms were relieved. Conclusion Parathyroidectomy is the treatment of choice for PHPT. Early diagnosis and treatment for PHPT can protect patients from multiple organs injury.

关 键 词：原发性甲状旁腺功能亢进症 诊断 手术治疗 

分 类 号：R653[医药卫生—外科学]