脂多糖诱导奶牛细胞因子及其他相关物质变化研究进展  

Progress on the Changes of the Cytokines and Other Relative Substances after the LPS Stimulation

作　　者：胡涛[1,2] 周凌云[1] 卜登攀[1] 张养东[1] 

机构地区：[1]中国农业科学院北京畜牧兽医研究所,动物营养学国家重点实验室,北京100193 [2]扬州大学动物科学技术学院,江苏扬州225009

出　　处：《华北农学报》2010年第B12期144-148,共5页Acta Agriculturae Boreali-Sinica

摘　　要：目前,奶牛的亚急性瘤胃酸中毒(SARA)的发生率较高,这是因为瘤胃中革兰氏阴性菌(GNB)崩解释放大量脂多糖(LPS)引起的。脂多糖刺激后,会导致一系列的细胞因子级联反应,相应的乳蛋白及其他物质也会发生变化,对奶牛生产产生了很不利的影响。笔者就脂多糖刺激对奶牛细胞因子、乳蛋白及其他物质的变化做一具体综述。The incidence rate of the Subacute ruminal acidosis（SARA） in cow is relatively high,it was because of the Gram negative bacteria（GNB） in the rumen have released a lot of lipopolysaccharide（LPS）.After the stimulate of the LPS,it will cause a series of cytokines cascade reaction,and the related milk protein and other substances will have some changes,it has a very bad effect on the milk production.This paper will summarize the changes of the cytokines,milk proteins and ather substances that after the LPS stimulation.

关 键 词：奶牛 SARA 脂多糖 细胞因子 

分 类 号：S852.2[农业科学—基础兽医学]