成纤维细胞生长因子21治疗代谢性疾病的潜在作用的研究进展  

Progress in potential therapeutic effects of the fibroblast growth factor 21 on the metabolic diseases

作　　者：闫欣欣[1] 林灼锋[1] 林绍强[1] 

机构地区：[1]温州医学院药学院生物制药教研室,浙江温州325035

出　　处：《中国临床药理学杂志》2010年第12期954-956,共3页The Chinese Journal of Clinical Pharmacology

摘　　要：成纤维细胞生长因子21(FGF21)与成纤维细胞生长因子家族的其他成员有着不同的生物学活性,其有调节代谢的重要功能,且有治疗代谢性疾病的潜在作用。为此本文对FGF21其研究现状和FGF21的信号途径进行了综述。It is found that fibroblast growth factor 21（FGF21）has different biological activity comparing with other members of FGFs and can regulate metabolism.Due to its potential therapeutic effect on metabolic diseases.FGF21 has been the new research focus in the world.This review mainly focuses on the advanced research achievement of FGF21 in animals and human being in addition its signal pathway.

关 键 词：成纤维细胞生长因子21 脂肪细胞 胰岛素 糖尿病 

分 类 号：R977.15[医药卫生—药品] R965.1[医药卫生—药学]